健康和神经血管疾病中大脑边界的免疫区。

IF 7.9 2区 医学 Q1 IMMUNOLOGY Seminars in Immunopathology Pub Date : 2023-05-01 Epub Date: 2023-05-03 DOI:10.1007/s00281-023-00992-6
Jennifer E Goertz, Lidia Garcia-Bonilla, Costantino Iadecola, Josef Anrather
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引用次数: 0

摘要

最近的证据表明,脑膜、脉络丛、脑周器官和颅骨骨髓中的颅缘免疫区与多种神经炎症和肿瘤性疾病有关。它们在高血压和中风等心血管疾病中的重要致病作用也已得到描述。在这篇综述中,我们将研究这些颅缘免疫龛的细胞组成、它们可能相互作用的潜在途径以及它们与心血管疾病相关的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Immune compartments at the brain's borders in health and neurovascular diseases.

Recent evidence implicates cranial border immune compartments in the meninges, choroid plexus, circumventricular organs, and skull bone marrow in several neuroinflammatory and neoplastic diseases. Their pathogenic importance has also been described for cardiovascular diseases such as hypertension and stroke. In this review, we will examine the cellular composition of these cranial border immune niches, the potential pathways through which they might interact, and the evidence linking them to cardiovascular disease.

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来源期刊
Seminars in Immunopathology
Seminars in Immunopathology 医学-病理学
CiteScore
19.80
自引率
2.20%
发文量
69
审稿时长
12 months
期刊介绍: The aim of Seminars in Immunopathology is to bring clinicians and pathologists up-to-date on developments in the field of immunopathology.For this purpose topical issues will be organized usually with the help of a guest editor.Recent developments are summarized in review articles by authors who have personally contributed to the specific topic.
期刊最新文献
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