{"title":"从西洋参果实中提取一种新的八酚型人参皂苷。","authors":"Yinping Jin, Zhengyi Qu, Shifeng Pang, Zheng Li, Yingping Wang, Hao Zhang","doi":"10.1080/14786419.2023.2252566","DOIUrl":null,"url":null,"abstract":"<p><p>A new ocotillol-type ginsenoside, named pseudoginsenoside F<sub>12</sub> (<b>1</b>), was isolated from American ginseng berry, whose structure was elucidated as 6-<i>O</i>-[<i>α</i>-L-2,3-epoxy-rhamnopyranosyl-(1-2)-<i>β</i>-D-glucopyranosyl]-dammar-20S,24R-epoxy-3<i>β</i>, 6<i>α</i>,12<i>β</i>,25-tetraol. In addition, the known alkaloids <i>β</i>-carboline-1-carboxylic acid (<b>2</b>) and anoectochine (<b>3</b>) were isolated for the first time from the Araliaceae family. The new compound <b>1</b> was evaluated for cytotoxicity against MDA-MB-231 breast cancer cell line.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"73-78"},"PeriodicalIF":1.9000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A new ocotillol-type ginsenoside from American ginseng berry.\",\"authors\":\"Yinping Jin, Zhengyi Qu, Shifeng Pang, Zheng Li, Yingping Wang, Hao Zhang\",\"doi\":\"10.1080/14786419.2023.2252566\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A new ocotillol-type ginsenoside, named pseudoginsenoside F<sub>12</sub> (<b>1</b>), was isolated from American ginseng berry, whose structure was elucidated as 6-<i>O</i>-[<i>α</i>-L-2,3-epoxy-rhamnopyranosyl-(1-2)-<i>β</i>-D-glucopyranosyl]-dammar-20S,24R-epoxy-3<i>β</i>, 6<i>α</i>,12<i>β</i>,25-tetraol. In addition, the known alkaloids <i>β</i>-carboline-1-carboxylic acid (<b>2</b>) and anoectochine (<b>3</b>) were isolated for the first time from the Araliaceae family. The new compound <b>1</b> was evaluated for cytotoxicity against MDA-MB-231 breast cancer cell line.</p>\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":\" \",\"pages\":\"73-78\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/14786419.2023.2252566\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/9/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2023.2252566","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/4 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A new ocotillol-type ginsenoside from American ginseng berry.
A new ocotillol-type ginsenoside, named pseudoginsenoside F12 (1), was isolated from American ginseng berry, whose structure was elucidated as 6-O-[α-L-2,3-epoxy-rhamnopyranosyl-(1-2)-β-D-glucopyranosyl]-dammar-20S,24R-epoxy-3β, 6α,12β,25-tetraol. In addition, the known alkaloids β-carboline-1-carboxylic acid (2) and anoectochine (3) were isolated for the first time from the Araliaceae family. The new compound 1 was evaluated for cytotoxicity against MDA-MB-231 breast cancer cell line.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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