血液透析患者营养不良炎症评分及膳食脂肪质量指标与心血管疾病的关系

IF 0.8 4区 医学 Q4 UROLOGY & NEPHROLOGY Iranian journal of kidney diseases Pub Date : 2023-05-01
Zahra Mirali, Golnaz Majdizadeh, Mahsa Baghbani, Shahrzad Ossareh, Nooshin Dalili, Ariyo Movahedi
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引用次数: 0

摘要

简介:营养不良-炎症-动脉粥样硬化是一个独立的危险因素,是透析患者最重要的死亡原因,约占总死亡人数的50%。此外,终末期肾病患者心血管引起的高死亡率不能完全归因于心血管(CVD)危险因素。研究表明,氧化应激、炎症、骨骼疾病、血管僵硬和能量蛋白损失等危险因素与这些患者的心血管疾病及其相关死亡率密切相关。此外,膳食脂肪是心血管疾病的关键因素。本研究旨在确定CKD患者营养不良-炎症与脂肪质量指标之间的关系。方法:本研究于2020 - 2021年在伊朗德黑兰Hashminejad肾脏中心附属教学医院进行血液透析患者121例,年龄20 ~ 80岁。收集了一般特征和人体测量指标的数据。采用MIS和DMS问卷评估营养不良-炎症评分,采用24小时回忆问卷测量饮食摄入量。结果:121例血液透析患者中,男性占57.3%,女性占42.7%。不同心脏病组间人体统计学特征差异无统计学意义(P > 0.05)。血透患者营养不良-炎症与心脏疾病指标无显著相关性(P > 0.05)。此外,膳食脂肪质量指数与心脏病无相关性(P > 0.05)。结论:本研究中,血液透析患者的营养不良-炎症指数、膳食脂肪质量指数与心脏疾病无显著相关性。需要进一步的研究才能得出切实的结论。DOI: 10.52547 / ijkd.7280。
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Relationship Between Malnutrition Inflammation Score and Dietary Fat Quality Indices with Cardiovascular Diseases in Hemodialysis Patients.

Introductions: Malnutrition-inflammation-atherosclerosis is an independent risk factor and the most significant cause of death in dialysis patients, accounting for about 50% of deaths in the population. Moreover, the high incidence of cardiovascular-induced mortality in patients with end-stage kidney disease cannot be fully attributed to cardiovascular (CVD) risk factors only. Studies suggest that risk factors such as oxidative stress, inflammation, bone disorders, vascular stiffness, and energy protein loss are closely related to CVD and its associated mortality in these patients. Moreover, dietary fat is a crucial factor in CVD. This study focused on determining the relationship between malnutrition-inflammation and fat quality indicators among CKD patients.

Methods: This study was conducted on 121 hemodialysis patients aged 20 to 80 years in a teaching hospital affiliated to Hashminejad kidney center in Tehran, Iran during 2020 to 2021. Data on general characteristics and anthropometric indices were collected. The malnutrition-inflammation score was assessed by using MIS and DMS questionnaires and dietary intake was measured by a 24-hour recall questionnaire.

Results: Out of 121 hemodialysis patients participating in the study, 57.3% were male and 42.7% were female. Anthropometric demographic characteristics showed no significant difference among diverse groups with heart disease (P > .05). There was no significant relationship between malnutrition-inflammation and heart disease indices in hemodialysis patients (P > .05). Furthermore, there was no correlation between the dietary fat quality index and heart disease (P > .05).

Conclusion: In this study, there was no significant relationship between the malnutrition-inflammation index and the dietary fat quality index with cardiac disease in hemodialysis patients. Further studies are needed to have a tangible conclusion.  DOI: 10.52547/ijkd.7280.

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来源期刊
Iranian journal of kidney diseases
Iranian journal of kidney diseases UROLOGY & NEPHROLOGY-
CiteScore
2.50
自引率
0.00%
发文量
43
审稿时长
6-12 weeks
期刊介绍: The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.
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