纳米材料在抗菌和抗病毒治疗中的应用前景。

IF 2.7 Q3 MICROBIOLOGY AIMS Microbiology Pub Date : 2023-01-01 DOI:10.3934/microbiol.2023024
Ashok Chakraborty, Anil Diwan, Jayant Tatake
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引用次数: 0

摘要

近年来,由于抗生素耐药性的证据越来越多,纳米材料的研究在微生物学领域得到了探索。纳米材料可以是无机的也可以是有机的,它们可以从植物或动物的天然产物中合成。纳米材料的治疗应用非常广泛,从疾病诊断到药物靶向递送。纳米颗粒的广谱抗病毒和抗菌活性也很明显。纳米颗粒的表面积与体积之比很高,这使得它们在许多方面成为一种有利的药物载体。有效地利用各种材料合成纳米粒子赋予它们许多特异性,以满足特定治疗策略的要求。纳米颗粒的潜在治疗用途及其对细菌、真菌和病毒感染的作用机制是本综述的重点。此外,它们的潜在优点,缺点,局限性和副作用也包括在这里。研究人员正在描述可能对受试者或环境造成严重毒性的纳米药物的暴露途径。事实上,使用纳米药物的社会伦理问题给科学家们提出了一个严重的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Prospect of nanomaterials as antimicrobial and antiviral regimen.

In recent years studies of nanomaterials have been explored in the field of microbiology due to the increasing evidence of antibiotic resistance. Nanomaterials could be inorganic or organic, and they may be synthesized from natural products from plant or animal origin. The therapeutic applications of nano-materials are wide, from diagnosis of disease to targeted delivery of drugs. Broad-spectrum antiviral and antimicrobial activities of nanoparticles are also well evident. The ratio of nanoparticles surface area to their volume is high and that allows them to be an advantageous vehicle of drugs in many respects. Effective uses of various materials for the synthesis of nanoparticles impart much specificity in them to meet the requirements of specific therapeutic strategies. The potential therapeutic use of nanoparticles and their mechanisms of action against infections from bacteria, fungi and viruses were the focus of this review. Further, their potential advantages, drawbacks, limitations and side effects are also included here. Researchers are characterizing the exposure pathways of nano-medicines that may cause serious toxicity to the subjects or the environment. Indeed, societal ethical issues in using nano-medicines pose a serious question to scientists beyond anything.

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来源期刊
AIMS Microbiology
AIMS Microbiology MICROBIOLOGY-
CiteScore
7.00
自引率
2.10%
发文量
22
审稿时长
8 weeks
期刊最新文献
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