巴基斯坦裔儿童/青少年慢性髓细胞白血病患者对酪氨酸激酶抑制剂的反应。

Syed Yar Muhammad Shah, Darakhshanda Nawaz, Aiman Usman Lodhi, Jawad Ur Rehman, Rehman Bahadar, Zaheer Ahmad, Faizan Banaras
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引用次数: 0

摘要

慢性粒细胞性白血病是一种骨髓产生过多白细胞的疾病。它在中年更常见,在儿童中发病率很低。伊马替尼是治疗慢性粒细胞白血病的标准一线药物。它改善了预后,副作用较小。我们感兴趣的是强调它在儿科年龄组中的作用。我们介绍了一个对伊马替尼有反应的慢性髓细胞白血病患者的病例系列。由于慢性髓细胞白血病在这个年龄段的发病率很低,探索治疗方式在paeds组中作用的研究有限。我们的病例系列强调了伊马替尼在治疗和改善该年龄组疾病预后方面的有效性。
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The Responsiveness Of Childhood/Adolescent Chronic Myeloid Leukaemia Patients Of Pakistani Origin To Tyrosine Kinase Inhibitor.

Chronic myelogenous leukaemia is a disease in which bone marrow produces too many white blood cells. It is more common in middle age and its incidence is rare in children. Imatinib is the standard first-line treatment in chronic myeloid leukaemia. It improved the prognosis with lesser side effects. Our point of interest is to highlight its role in the paediatric age group. we present case series of a patient with chronic myeloid leukaemia responsive to imatinib. Because of the rare incidence of chronic myeloid leukaemia in this age room limited studies to explore the role of treatment modalities in the paeds group. Our case series highlights imatinib's effectiveness in treatment and improving the prognosis of the disease in this age group.

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REFRACTORY SARCOIDOSIS Cytogenetic Profiling In Paediatric Acute Leukaemia; A Report On 746 Newly Diagnosed Paediatric Cases Analyzing The Spectrum Of Recurring Chromosomal Rearrangements In B Cell Lymphoblastic And Acute Myeloid Leukaemia. Risk Loci For Chronic Obstructive Disease Reside On Chromosome 14: A Case-Control Study On The Pakistani Population. Giant Penoscrotal Lymphedema: Planning And Surgical Technique To Treat A Rare Debilitating Disease. Management And Assessment Of Indeterminate (U3) Thyroid Nodules: A 5-Year Multisite Retrospective Study.
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