{"title":"类固醇难治性急性移植物抗宿主病的治疗与护理。","authors":"Naomi Cazeau, Stephany L Rodriguez","doi":"10.1188/23.CJON.397-403","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Acute graft-versus-host disease (aGVHD) is a significant complication for patients who receive allogeneic stem cell transplantation. Patients whose aGVHD is refractory to corticosteroids face additional complications.</p><p><strong>Objectives: </strong>This article provides foundational knowledge on steroid-refractory (SR) aGVHD, current treatment options, and related supportive care.</p><p><strong>Methods: </strong>Therapies for patients with SR aGVHD are summarized, along with supportive care recommendations and a review of related nursing considerations.</p><p><strong>Findings: </strong>Current treatment and research on SR aGVHD offer opportunities for improved clinical outcomes for these patients. Nursing knowledge of the pathophysiology, treatment, and supportive care for patients with SR aGVHD is integral to the provision of optimal nursing care for a complex population of patients.</p>","PeriodicalId":10350,"journal":{"name":"Clinical journal of oncology nursing","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Treatment and Nursing for Steroid-Refractory Acute Graft-Versus-Host Disease.\",\"authors\":\"Naomi Cazeau, Stephany L Rodriguez\",\"doi\":\"10.1188/23.CJON.397-403\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Acute graft-versus-host disease (aGVHD) is a significant complication for patients who receive allogeneic stem cell transplantation. Patients whose aGVHD is refractory to corticosteroids face additional complications.</p><p><strong>Objectives: </strong>This article provides foundational knowledge on steroid-refractory (SR) aGVHD, current treatment options, and related supportive care.</p><p><strong>Methods: </strong>Therapies for patients with SR aGVHD are summarized, along with supportive care recommendations and a review of related nursing considerations.</p><p><strong>Findings: </strong>Current treatment and research on SR aGVHD offer opportunities for improved clinical outcomes for these patients. Nursing knowledge of the pathophysiology, treatment, and supportive care for patients with SR aGVHD is integral to the provision of optimal nursing care for a complex population of patients.</p>\",\"PeriodicalId\":10350,\"journal\":{\"name\":\"Clinical journal of oncology nursing\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-07-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical journal of oncology nursing\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1188/23.CJON.397-403\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NURSING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical journal of oncology nursing","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1188/23.CJON.397-403","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NURSING","Score":null,"Total":0}
Treatment and Nursing for Steroid-Refractory Acute Graft-Versus-Host Disease.
Background: Acute graft-versus-host disease (aGVHD) is a significant complication for patients who receive allogeneic stem cell transplantation. Patients whose aGVHD is refractory to corticosteroids face additional complications.
Objectives: This article provides foundational knowledge on steroid-refractory (SR) aGVHD, current treatment options, and related supportive care.
Methods: Therapies for patients with SR aGVHD are summarized, along with supportive care recommendations and a review of related nursing considerations.
Findings: Current treatment and research on SR aGVHD offer opportunities for improved clinical outcomes for these patients. Nursing knowledge of the pathophysiology, treatment, and supportive care for patients with SR aGVHD is integral to the provision of optimal nursing care for a complex population of patients.
期刊介绍:
The Clinical Journal of Oncology Nursing (CJON) is an official publication of the Oncology Nursing Society (ONS) and is directed to the practicing nurse specializing in the care of patients with an actual or potential diagnosis of cancer. CJON is a vehicle to promote the mission of ONS, which is to advance excellence in oncology nursing and quality cancer care. The CJON mission is twofold: to provide practical information necessary to care for patients and their families across the cancer continuum and to develop publication skills in oncology nurses.