{"title":"老年患者的肌萎缩性肥胖和高血压:病理生理学和管理策略的叙述性综述。","authors":"Mihaela Jurdana, Lovro Žiberna","doi":"10.4415/ANN_23_03_10","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Sarcopenic obesity and hypertension are a public health problem that is increasing worldwide due to the progressive aging of the population and the increasing prevalence of obesity and physical inactivity. Sarcopenic obesity is characterized by the simultaneous presence of sarcopenia (loss of muscle mass) and adiposity (increase in fat mass). Because symptoms are not specific, sarcopenic obesity remains largely undiagnosed. This review explores the latest research on sarcopenic obesity and its association with hypertension, with a focus on arterial stiffness.</p><p><strong>Methods: </strong>A comprehensive narrative review was conducted by systematically searching PubMed and Scopus databases for relevant scientific literature.</p><p><strong>Results: </strong>Sarcopenic obesity and hypertension are closely linked, sharing common factors such as inflammation, insulin resistance, and oxidative stress, with arterial stiffness playing a crucial role.</p><p><strong>Discussion: </strong>Given the lack of specific symptoms for sarcopenic obesity, early diagnosis and management are crucial. Treatment strategies should prioritize weight loss, adequate protein intake, and regular physical activity. Further investigation is warranted for pharmacological interventions.</p><p><strong>Conclusion: </strong>Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.</p>","PeriodicalId":8246,"journal":{"name":"Annali dell'Istituto superiore di sanita","volume":"59 3","pages":"231-239"},"PeriodicalIF":1.1000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies.\",\"authors\":\"Mihaela Jurdana, Lovro Žiberna\",\"doi\":\"10.4415/ANN_23_03_10\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Sarcopenic obesity and hypertension are a public health problem that is increasing worldwide due to the progressive aging of the population and the increasing prevalence of obesity and physical inactivity. Sarcopenic obesity is characterized by the simultaneous presence of sarcopenia (loss of muscle mass) and adiposity (increase in fat mass). Because symptoms are not specific, sarcopenic obesity remains largely undiagnosed. This review explores the latest research on sarcopenic obesity and its association with hypertension, with a focus on arterial stiffness.</p><p><strong>Methods: </strong>A comprehensive narrative review was conducted by systematically searching PubMed and Scopus databases for relevant scientific literature.</p><p><strong>Results: </strong>Sarcopenic obesity and hypertension are closely linked, sharing common factors such as inflammation, insulin resistance, and oxidative stress, with arterial stiffness playing a crucial role.</p><p><strong>Discussion: </strong>Given the lack of specific symptoms for sarcopenic obesity, early diagnosis and management are crucial. Treatment strategies should prioritize weight loss, adequate protein intake, and regular physical activity. Further investigation is warranted for pharmacological interventions.</p><p><strong>Conclusion: </strong>Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.</p>\",\"PeriodicalId\":8246,\"journal\":{\"name\":\"Annali dell'Istituto superiore di sanita\",\"volume\":\"59 3\",\"pages\":\"231-239\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annali dell'Istituto superiore di sanita\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4415/ANN_23_03_10\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annali dell'Istituto superiore di sanita","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4415/ANN_23_03_10","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Sarcopenic obesity and hypertension in elderly patients: a narrative review of pathophysiology and management strategies.
Introduction: Sarcopenic obesity and hypertension are a public health problem that is increasing worldwide due to the progressive aging of the population and the increasing prevalence of obesity and physical inactivity. Sarcopenic obesity is characterized by the simultaneous presence of sarcopenia (loss of muscle mass) and adiposity (increase in fat mass). Because symptoms are not specific, sarcopenic obesity remains largely undiagnosed. This review explores the latest research on sarcopenic obesity and its association with hypertension, with a focus on arterial stiffness.
Methods: A comprehensive narrative review was conducted by systematically searching PubMed and Scopus databases for relevant scientific literature.
Results: Sarcopenic obesity and hypertension are closely linked, sharing common factors such as inflammation, insulin resistance, and oxidative stress, with arterial stiffness playing a crucial role.
Discussion: Given the lack of specific symptoms for sarcopenic obesity, early diagnosis and management are crucial. Treatment strategies should prioritize weight loss, adequate protein intake, and regular physical activity. Further investigation is warranted for pharmacological interventions.
Conclusion: Sarcopenic obesity and hypertension present significant challenges to global public health. Addressing arterial stiffness is paramount in managing these conditions effectively. Lifestyle modifications, including weight management and physical activity, remain central to the treatment of sarcopenic obesity, while additional research is needed to explore potential pharmacological options.
期刊介绍:
Annali dell’Istituto Superiore di Sanità is a peer reviewed quarterly science journal which publishes research articles in biomedicine, translational research and in many other disciplines of the health sciences. The journal includes the following material: original articles, reviews, commentaries, editorials, brief and technical notes, book reviews.
The publication of Monographic Sections has been discontinued. In case you wish to present a small number of coordinated contributions on specific themes concerning priorities in public health, please contact the Editorial office.
The journal is in English.