重庆居民膳食铅暴露的概率风险评估

Jiahui Chen, Jingrong Chen, Ping Feng, Cheng Long, Ailin Wu, Qinpei Zou, Shuquan Luo, Jian Zhao, Huadong Zhang, Xuemei Lian, Jiao Huo
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引用次数: 0

摘要

目的:了解重庆市商品食品中铅污染情况,评价重庆市居民膳食铅暴露的健康风险。方法:从重庆市食品安全风险监测系统中获取2016 - 2020年11类2347份含铅食品样品的铅浓度数据。消费数据来源于2018年重庆市中国健康与营养调查项目(3天,24 h膳食召回调查)。采用蒙特卡罗模拟法计算重庆市居民膳食铅暴露量,并采用暴露边际法评价人群健康风险。结果:11类2347份食品样品中铅的平均含量在0.0328 ~ 0.0363 mg/kg之间,总体检出率为58.5%。3 ~ 6岁、7 ~ 17岁、18 ~ 59岁、≥60岁人群铅平均摄入量分别为0.935 ~ 1.070、0.600 ~ 0.684、0.367 ~ 0.416、0.369 ~ 0.419 μg/(kg·BW·d);高铅暴露水平(P95)分别为1.642 ~ 1.852、1.147 ~ 1.299、0.651 ~ 0.729、0.659 ~ 0.740 μg/(kg·BW·d)。3 ~ 6岁和7 ~ 17岁年龄组铅的MOE值均小于1。18 ~ 59岁和≥60岁的铅的平均MOE值大于1。谷物及其制品、蔬菜及其制品、肉类及肉制品是膳食铅暴露的主要来源,占膳食铅暴露总量的85%以上。结论:重庆市居民铅存在潜在健康风险。
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[Probabilistic risk assessment of dietary exposure to lead among Chongqing residents].

Objective: To investigate lead contamination in commercial foods in Chongqing City, and to assess the health risk of dietary lead exposure of residents in Chongqing City.

Methods: Lead concentration data was obtained from the food safety risk monitoring system, which included a total of 2347 lead-containing food samples in 11 categories in Chongqing from 2016 to 2020. Consumption data was derived from the China Health and Nutrition Survey Project in Chongqing in 2018(3 day, 24 h dietary recall survey). The dietary exposure to lead of residents in Chongqing was calculated by the Monte Carlo simulation method and the margin of exposure(MOE) method was used to evaluate the health risk of the population.

Results: The average content of lead in 2347 food samples from 11 categories ranged from 0.0328 to 0.0363 mg/kg, with an overall detection rate of 58.5%. For people aged between 3-6, 7-17, 18-59, and ≥ 60 years, the mean dietary lead intakes in Chongqing were 0.935-1.070, 0.600-0.684, 0.367-0.416, 0.369-0.419 μg/(kg·BW·d), respectively; and the high levels of dietary lead exposure(P95) were 1.642-1.852, 1.147-1.299, 0.651-0.729, 0.659-0.740 μg/(kg·BW·d), respectively. MOE values for lead were less than 1 for age groups 3-6 and 7-17 years. Mean MOE values for lead were greater than 1 for ages 18 to 59 and ≥ 60. Cereals and their products, vegetables and their products, and meat and meat products were the main sources of dietary lead exposure, accounting for more than 85% of the total dietary lead exposure.

Conclusion: There are potential health risks of lead for residents in Chongqing.

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