女性型脱发和多囊卵巢综合征:不仅仅是多毛症。

IF 2.6 3区 医学 Q3 ENDOCRINOLOGY & METABOLISM Current Opinion in Endocrinology & Diabetes and Obesity Pub Date : 2022-12-01 DOI:10.1097/MED.0000000000000777
Victoria S Jiang, Spencer D Hawkins, Amy McMichael
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引用次数: 1

摘要

综述目的:探讨多囊卵巢综合征(PCOS)患者雄激素性脱发的诊断、治疗和临床意义的最新进展。最新发现:多囊卵巢综合征诊断仍然是育龄妇女不孕的最常见原因,是这一人群中最常见的内分泌疾病。女性型脱发(FPHL)已被认为与PCOS患者相关且在PCOS患者中更为常见,然而,关于FPHL对PCOS患者影响的研究有限。虽然高雄激素血症与FPHL有关,但由于FPHL可以与正常的生化雄激素标志物一起存在,因此病理生理学仍不清楚。治疗可能是复杂的,因为促进头发生长的普通治疗会加剧不想要的多毛症,这可以通过美容治疗来克服。新的二线治疗选择,如低水平激光治疗和富血小板血浆已经出现,有限的数据支持疗效。摘要:多囊卵巢综合征是一种复杂的内分泌疾病,具有重要的妇科、皮肤和代谢影响,需要多学科合作和护理。在开始任何治疗之前,应充分讨论生殖目标,因为多囊卵巢综合征是育龄妇女不孕的最常见原因。
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Female pattern hair loss and polycystic ovarian syndrome: more than just hirsutism.

Purpose of review: To explore the recent updates in the diagnosis, management, and clinical implications of androgenic alopecia among patients diagnosed with polycystic ovarian syndrome (PCOS).

Recent findings: PCOS diagnosis continues to be the most common cause of infertility among reproductively aged women, serving as the most common endocrinopathy among this population. Female pattern hair loss (FPHL) has been seen to be associated and more common among patients with PCOS, however, there are limited studies examining the impact of FPHL among PCOS patients. Although hyperandrogenism is associated with FPHL, the pathophysiology continues to be unclear as FPHL can be present with normal biochemical androgen markers. Treatment can be complex, as common treatments to promote hair growth can exacerbate undesired hirsutism, which can be overcome by cosmetic treatments. New second-line treatment options such as low level laser therapy and platelet rich plasma have been emerging, with limited data supporting efficacy.

Summary: PCOS is a complex endocrinological disorder that has significant gynecologic, cutaneous, and metabolic implications that require multidisciplinary collaboration and care. Reproductive goals should be thoroughly discussed prior to starting any treatment, as PCOS is the most common cause of infertility among reproductively-aged women.

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来源期刊
CiteScore
5.80
自引率
3.10%
发文量
128
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​​Current Opinion in Endocrinology, Diabetes and Obesity delivers a broad-based perspective on the most recent and exciting developments in the field from across the world. Published bimonthly and featuring twelve key topics – including androgens, gastrointestinal hormones, diabetes and the endocrine pancreas, and neuroendocrinology – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.
期刊最新文献
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