{"title":"雷莫尼棒状杆菌（Corynebacterium ramonii sp.nov.），白喉棒状杆菌物种复合体的一个新的产毒成员。","authors":"Chiara Crestani , Gabriele Arcari , Annie Landier , Virginie Passet , Dorian Garnier , Sylvie Brémont , Nathalie Armatys , Annick Carmi-Leroy , Julie Toubiana , Edgar Badell , Sylvain Brisse","doi":"10.1016/j.resmic.2023.104113","DOIUrl":null,"url":null,"abstract":"<div><p>The <span><em>Corynebacterium</em><em> diphtheriae</em></span> species complex comprises seven bacterial species, including <span><em>Corynebacterium ulcerans</em></span><span>, a zoonotic pathogen from multiple animal species. In this work, we characterise phenotypically and genotypically isolates belonging to two </span><em>C. ulcerans</em><span> lineages<span>. Results from phylogenetic analyses, </span></span><em>in silico</em> DNA–DNA hybridization (DDH) and MALDI-TOF spectra differentiate lineage 2 from <em>C. ulcerans</em> lineage 1, which, together with their distinct transmission dynamics (probable human-to-human vs animal-to-human), indicates that lineage 2 is a separate <em>Corynebacterium</em> species, which we propose to name <em>Corynebacterium ramonii</em>. This species is of particular medical interest considering that its human-to-human transmission is likely, and that some <em>C. ramonii</em> isolates carry the diphtheria toxin gene.</p></div>","PeriodicalId":21098,"journal":{"name":"Research in microbiology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Corynebacterium ramonii sp. nov., a novel toxigenic member of the Corynebacterium diphtheriae species complex\",\"authors\":\"Chiara Crestani , Gabriele Arcari , Annie Landier , Virginie Passet , Dorian Garnier , Sylvie Brémont , Nathalie Armatys , Annick Carmi-Leroy , Julie Toubiana , Edgar Badell , Sylvain Brisse\",\"doi\":\"10.1016/j.resmic.2023.104113\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The <span><em>Corynebacterium</em><em> diphtheriae</em></span> species complex comprises seven bacterial species, including <span><em>Corynebacterium ulcerans</em></span><span>, a zoonotic pathogen from multiple animal species. In this work, we characterise phenotypically and genotypically isolates belonging to two </span><em>C. ulcerans</em><span> lineages<span>. Results from phylogenetic analyses, </span></span><em>in silico</em> DNA–DNA hybridization (DDH) and MALDI-TOF spectra differentiate lineage 2 from <em>C. ulcerans</em> lineage 1, which, together with their distinct transmission dynamics (probable human-to-human vs animal-to-human), indicates that lineage 2 is a separate <em>Corynebacterium</em> species, which we propose to name <em>Corynebacterium ramonii</em>. This species is of particular medical interest considering that its human-to-human transmission is likely, and that some <em>C. ramonii</em> isolates carry the diphtheria toxin gene.</p></div>\",\"PeriodicalId\":21098,\"journal\":{\"name\":\"Research in microbiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research in microbiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0923250823000888\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research in microbiology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0923250823000888","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Corynebacterium ramonii sp. nov., a novel toxigenic member of the Corynebacterium diphtheriae species complex
The Corynebacterium diphtheriae species complex comprises seven bacterial species, including Corynebacterium ulcerans, a zoonotic pathogen from multiple animal species. In this work, we characterise phenotypically and genotypically isolates belonging to two C. ulcerans lineages. Results from phylogenetic analyses, in silico DNA–DNA hybridization (DDH) and MALDI-TOF spectra differentiate lineage 2 from C. ulcerans lineage 1, which, together with their distinct transmission dynamics (probable human-to-human vs animal-to-human), indicates that lineage 2 is a separate Corynebacterium species, which we propose to name Corynebacterium ramonii. This species is of particular medical interest considering that its human-to-human transmission is likely, and that some C. ramonii isolates carry the diphtheria toxin gene.
期刊介绍：
Research in Microbiology is the direct descendant of the original Pasteur periodical entitled Annales de l''Institut Pasteur, created in 1887 by Emile Duclaux under the patronage of Louis Pasteur. The Editorial Committee included Chamberland, Grancher, Nocard, Roux and Straus, and the first issue began with Louis Pasteur''s "Lettre sur la Rage" which clearly defines the spirit of the journal:"You have informed me, my dear Duclaux, that you intend to start a monthly collection of articles entitled "Annales de l''Institut Pasteur". You will be rendering a service that will be appreciated by the ever increasing number of young scientists who are attracted to microbiological studies. In your Annales, our laboratory research will of course occupy a central position, but the work from outside groups that you intend to publish will be a source of competitive stimulation for all of us."That first volume included 53 articles as well as critical reviews and book reviews. From that time on, the Annales appeared regularly every month, without interruption, even during the two world wars. Although the journal has undergone many changes over the past 100 years (in the title, the format, the language) reflecting the evolution in scientific publishing, it has consistently maintained the Pasteur tradition by publishing original reports on all aspects of microbiology.
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