急性A型主动脉夹层修复的专业化:结果和挑战

IF 2.6 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2023-09-01 DOI:10.1053/j.semtcvs.2022.05.005
Elizabeth L. Norton MD, MS , Linda Farhat MS , Xiaoting Wu PhD , Karen M. Kim MD , Shinichi Fukuhara MD , Himanshu J. Patel MD , George Michael Deeb MD , Bo Yang MD, PhD
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引用次数: 0

摘要

随着心脏外科领域的专业化程度不断提高,以及许多领域的病例数量与手术结果之间的积极关系,研究了专职主动脉外科医生进行急性a型主动脉夹层(ATAAD)修复的概念。从1996年到2014年,436名患者接受了ATAAD的开放手术修复,随后根据外科医生的亚专业划分为主动脉外科医生(AS,n=401)和非主动脉外科医生(NAS,n=35)。每位主动脉外科医生平均每年进行13次ATAAD修复手术。两组患者术前合并症相似。术中,AS组进行了36%的主动脉根部置换术,NAS组为23%,P=0.012,1/2/3区主动脉弓置换术为36%,NAS组的26%,P=0.020)。术后,AS组的结果明显更好,包括术中死亡率(1.2%对5.7%)、30天死亡率(6.5%对17%)和综合结果(23%对46%)。多变量逻辑回归显示,NAS是30天死亡率的危险因素,比值比(OR)为4.4(P=0.03),COPD(OR=4.0,P=0.046)和心源性休克(OR=13.4,P<;0.0001)也是如此。as组的10年生存率为66%,NAS组为46%,P=0.02。NAS(HR=2.2)、年龄(危险比(HR)=1.05)、COPD(HR=1.96)、急性卒中(HR=3.0)和纽约心脏协会III或IV级(HR=1.75)是长期死亡率的重要危险因素。亚专业主动脉外科医生管理ATAAD可改善短期和长期结果。我们的专业可以考虑由大容量主动脉外科医生进行ATAAD修复,以获得更好的患者结果。
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Specialization in Acute Type A Aortic Dissection Repair: The Outcomes and Challenges

With increasing specialization within the field of cardiac surgery and a positive relationship between case volume and surgical outcomes in many areas, the concept of dedicated aortic surgeons performing acute type A aortic dissection (ATAAD) repair was investigated. From 1996 to 2014, 436 patients underwent open surgical repair of an ATAAD and were subsequently divided based on surgeon subspecialization, aortic-surgeon (AS, n = 401) vs non-aortic-surgeon (NAS, n = 35). Each aortic surgeon performed an average of 13 ATAAD repair operations per year. Preoperative comorbidities were similar between groups. Intraoperatively, the AS group had 36% aortic root replacement vs 23% in the NAS group, P = 0.12, and 36% zone 1/2/3 arch replacement vs 26% in the NAS group, P = 0.20). Postoperatively, the AS group had significantly better outcomes, including intraoperative mortality (1.2% vs 5.7%), 30-day mortality (6.5% vs 17%), and composite outcomes (23% vs 46%). Multivariable logistic regression showed NAS was a risk factor for 30-day mortality with an odds ratio (OR) of 4.4 (P = 0.03), as were COPD (OR = 4.0, P = 0.046) and cardiogenic shock (OR = 13.4, P < 0.0001). The 10-year survival was 66% in the AS group vs 46% in the NAS group, P = 0.02. NAS (HR = 2.2), Age (hazard ratio (HR) = 1.05), COPD (HR = 1.96), acute stroke (HR = 3.0), and New York Heart Association class III or IV (HR = 1.75) were significant risk factors for long-term mortality. Managing ATAAD by subspecialized aortic surgeons resulted in improved short- and long-term outcomes. Our specialty could consider ATAAD repair by high-volume aortic surgeons for better patient outcomes.

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来源期刊
Seminars in Thoracic and Cardiovascular Surgery
Seminars in Thoracic and Cardiovascular Surgery Medicine-Pulmonary and Respiratory Medicine
CiteScore
5.80
自引率
0.00%
发文量
324
审稿时长
12 days
期刊介绍: Seminars in Thoracic and Cardiovascular Surgery is devoted to providing a forum for cardiothoracic surgeons to disseminate and discuss important new information and to gain insight into unresolved areas of question in the specialty. Each issue presents readers with a selection of original peer-reviewed articles accompanied by editorial commentary from specialists in the field. In addition, readers are offered valuable invited articles: State of Views editorials and Current Readings highlighting the latest contributions on central or controversial issues. Another prized feature is expert roundtable discussions in which experts debate critical questions for cardiothoracic treatment and care. Seminars is an invitation-only publication that receives original submissions transferred ONLY from its sister publication, The Journal of Thoracic and Cardiovascular Surgery. As we continue to expand the reach of the Journal, we will explore the possibility of accepting unsolicited manuscripts in the future.
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