遗传学与免疫学的动态界面:健康与疾病的未来前景

IF 5 3区 医学 Q1 GENETICS & HEREDITY Genes and immunity Pub Date : 2023-07-18 DOI:10.1038/s41435-023-00213-y
Abhishek D. Garg
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引用次数: 0

摘要

了解免疫过程的遗传基础及其在群体免疫遗传学和宿主-微生物相互作用影响下的整体动态一直是健康和疾病研究的核心。最近,随着高分辨率单细胞或空间全息技术的应用,我们对这些动态变化的理解发生了范式转变,这些技术促进了对健康或疾病免疫环境的深入理解。在《基因与免疫》(Genes & Immunity)杂志上,我们希望根据这些趋势对期刊进行改版,并将在免疫学和遗传学这些多学科交叉领域工作的研究人员聚集在一起,目的是在揭示新的免疫疗法或生物标志物模式的同时,推动基础知识和转化知识的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The dynamic interface of genetics and immunity: toward future horizons in health & disease
Understanding the genetic basis of immunological processes and their overall dynamics under the influence of population immunogenetics and host-microbe interactions has been at the core of health and disease research. Our understanding of these dynamics has recently undergone a paradigm shift with the application of high-resolution single cell or spatial omics technologies that have facilitated a deeper understanding of healthy or diseased immune milieu. At Genes & Immunity, we wish to revamp the journal to cater to these trends and bring together researchers working at these multidisciplinary interfaces of immunology and genetics, with the aim of advancing fundamental and translational knowledge while revealing new immunotherapy or biomarker modalities.
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来源期刊
Genes and immunity
Genes and immunity 医学-免疫学
CiteScore
8.90
自引率
4.00%
发文量
28
审稿时长
6-12 weeks
期刊介绍: Genes & Immunity emphasizes studies investigating how genetic, genomic and functional variations affect immune cells and the immune system, and associated processes in the regulation of health and disease. It further highlights articles on the transcriptional and posttranslational control of gene products involved in signaling pathways regulating immune cells, and protective and destructive immune responses.
期刊最新文献
Neoantigen-specific mRNA/DC vaccines for effective anticancer immunotherapy. Roles of TULA-family proteins in T cells and autoimmune diseases. Epigenetics behind CD8+ T cell activation and exhaustion. Predictable regulation of gut microbiome in immunotherapeutic efficacy of gastric cancer. Inorganic pyrophosphatase 1: a key player in immune and metabolic reprogramming in ankylosing spondylitis.
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