生物膜的微观力学。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-12-01 DOI:10.1007/s00232-022-00254-w
T Bhatia
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引用次数: 3

摘要

微力学技术在生物膜的表征中发挥着越来越重要的作用。膜的机械性能在整个细胞过程中起着重要的作用。脂质-蛋白生物膜在介观和纳米尺度上表现出横向异质性、结构域形成和形态变化。尝试介绍如何测量膜的材料性能。利用波动分析和微移管抽吸实验来量化膜的微观力学。生物膜的结构与功能之间的关系是现代生物学中一个重要的问题。这一概述要求更深入地了解细胞复杂性如何与脂质-蛋白膜的机械特性相关。机械性能可以影响细胞对粘附、运输、分化、增殖和迁移等过程的反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Micromechanics of Biomembranes.

Micromechanics techniques are playing an increasing role in characterization of biomembranes. The mechanical properties of membranes play an important role for a whole range of cellular processes. Lipid-protein biomembranes display lateral heterogeneity, domain formation, and morphological changes at mesoscopic and nanoscopic length scales. An attempt is made to introduce how membrane's material properties can be measured. Both fluctuation analysis and micro-pipette aspiration experiments have been used to quantify the micromechanics of membranes. The relationship between the structure and function of biomembranes is a critical concern in modern biology. This overview calls for a deeper understanding of how the cell complexity might be related to the mechanical properties of the lipid-protein membrane. Mechanical properties can influence cellular response to processes like adhesion, transport, differentiation, proliferation and migration.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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