种植体螺纹设计对植入扭矩和骨整合的影响:临床前模型。

E-B Benalcázar-Jalkh, V-V Nayak, C Gory, A Marquez-Guzman, E-T Bergamo, N Tovar, P-G Coelho, E-A Bonfante, L Witek
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引用次数: 1

摘要

背景:种植体的设计,包括宏观、微观和纳米几何特性,使种植体的骨整合成功。根据目前有关种植体设计的文献,当种植体的螺纹厚度增加时,所产生的细胞和骨愈合反应是未知的,这导致在设计有愈合室的种植体中增加接触面积。本研究的目的是利用一个成熟的临床前犬模型,评估两种不同螺纹轮廓的种植体设计对体内3周和6周骨整合参数和种植体稳定性的影响。材料与方法:将48个V型钛合金种植体按照其螺纹设计分为两组(D1= +0.1x/mm, D2= +0.15x/mm),内插于6只beagle的半径内。在放置时测量插入扭矩,在3周和6周愈合间隔后提取桡骨进行组织学处理。根据骨与种植体接触(%BIC)和种植体螺纹内骨面积占用率(%BAFO)进行组织学和组织形态学分析。统计分析通过线性混合模型与固定因素的时间和种植螺纹设计。结果:表面粗糙度分析显示,D1和D2种植体设计的Sa和Sq没有显著差异,这证实了两种种植体设计除了各自的螺纹轮廓外都是均匀的。对于插入扭矩,D1比D2低(分别为59.6±11.1和78.9±10.1 N⋅cm)。此外,D1和D2在两个时间点的组织学分析和组织形态计量参数没有显著差异。结论:两种螺纹轮廓在截骨术中都具有成功骨整合的同等潜力,D2在放置时具有更高的机械保留力,而不会有害骨吸收。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Impact of implant thread design on insertion torque and osseointegration: a preclinical model.

Background: Successful osseointegration of endosteal dental implants has been attributed to implant design, including the macro-, micro- and nano- geometric properties. Based on current literature pertaining to implant design, the resultant cellular and bone healing response is unknown when the thread thickness of the implants is increased, resulting in an increased contact area in implants designed with healing chambers. The aim of this study was to evaluate the effect of two implant designs with different thread profiles on the osseointegration parameters and implant stability at 3- and 6-weeks in vivo using a well-established preclinical dog model.

Material and methods: A total of 48 type V Ti alloy implants were divided in two groups according to their thread design (D1= +0.1x/mm and D2= +0.15x/mm) and placed in an interpolated fashion into the radii of six beagles. Insertion torque was measured at time of placement, radii were extracted for histological processing following 3- and 6-week healing intervals. Histologic and histomorphometric analyses were performed in terms of bone to implant contact (%BIC) and bone area fraction occupancy within implant threads (%BAFO). Statistical analyses were performed through a linear mixed model with fixed factors of time and implant thread design.

Results: Surface roughness analysis demonstrated no significant differences in Sa and Sq between D1 and D2 implant designs, which confirmed that both implant designs were homogenous except for their respective thread profiles. For insertion torque, statistically significant lower values were recorded for D1 in comparison to D2 (59.6 ± 11.1 and 78.9 ± 10.1 N⋅cm, respectively). Furthermore, there were no significant differences with respect to histological analysis and histomorphometric parameters, between D1 and D2 at both time points.

Conclusions: Both thread profiles presented equivalent potential to successfully osseointegrate in the osteotomies, with D2 yielding higher mechanical retention upon placement without detrimental bone resorption.

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来源期刊
CiteScore
4.50
自引率
0.00%
发文量
52
期刊介绍: 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology
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