甲状腺功能减退症患者脱发的皮肤镜检查结果。

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM International Journal of Endocrinology and Metabolism Pub Date : 2022-10-11 eCollection Date: 2022-10-01 DOI:10.5812/ijem-128938
Kaveh Gharaei Nejad, Behrang Motamed, Afagh Hassanzadeh Rad, Elahe Rafiee, Setila Dalili, Atrie Molaei
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引用次数: 0

摘要

背景介绍甲状腺激素对毛囊的生长和维护至关重要。许多研究评估了甲状腺疾病与脱发之间的关系。然而,还没有研究对甲减和脱发患者的皮肤镜结果进行评估:本研究旨在调查甲状腺功能减退症患者脱发的皮肤镜结果:这项横断面分析研究的对象是转诊至伊朗吉兰医科大学皮肤科诊所的脱发患者。甲减患者与同等数量的甲状腺功能正常者进行了比较。在记录了人口统计学和临床特征后,所有患者都接受了毛发皮肤镜检查:结果:共对 164 名甲状腺功能减退症脱发患者和非甲状腺功能减退症脱发患者进行了研究。两组患者的毛干异常(P < 0.001)和绒毛异常(P < 0.001)的频率明显不同。与鳞屑异常(P = 0.002)及其毛囊周围类型(P < 0.001)相关的皮肤镜结果在两组之间存在明显差异。甲状腺功能减退症患者的血管变化(P < 0.001)、毛囊周围同心型(P = 0.012)和毛囊间红环型(P = 0.005)明显更高。此外,根据多元逻辑回归模型,与甲状腺功能亢进症相比,甲状腺功能减退症患者出现毛干、毛鳞片和血管变化异常的几率分别增加了3.24、2.73和3.53:本研究结果令人鼓舞,我们可以在甲状腺功能减退症脱发患者的皮肤镜下发现可能的炎症迹象。由于缺乏有关这种新型诊断方法的证据,因此还需要进一步的研究。
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Dermoscopic Findings of Alopecia in Patients with Hypothyroidism.

Background: Thyroid hormones are essential for the growth and maintenance of hair follicles. Numerous studies have evaluated the relationship between thyroid disorders and hair loss. However, no study has assessed the dermoscopic results in patients with hypothyroidism and hair loss.

Objectives: This study aimed to investigate dermoscopic findings of alopecia in patients with hypothyroidism.

Methods: This analytic cross-sectional study was performed on patients with hair loss referred to dermatology clinics of Guilan University of Medical Sciences, Iran. Hypothyroid patients and an equal number of euthyroid individuals were compared. After recording the demographic and clinical characteristics, all patients were subjected to hair dermoscopy.

Results: A total of 164 patients with and without hypothyroidism with hair loss were studied. The frequency of hair shaft abnormalities (P < 0.001) and vellus hair (P < 0.001) significantly differed between the two groups. Dermoscopic findings related to scale abnormalities (P = 0.002) and their perifollicular type (P < 0.001) significantly differed between the groups. Vascular changes (P < 0.001), perifollicular concentric type (P = 0.012), and interfollicular red loops type (P = 0.005) were significantly higher in patients with hypothyroidism. Also, based on the multiple logistic regression model, the chance of abnormalities of the hair shaft, scales, and vascular changes increased by 3.24, 2.73, and 3.53, respectively, in hypothyroidism compared to euthyroidism.

Conclusions: Regarding the promising results of this study, we could detect possible dermoscopic signs of inflammation in hypothyroid patients with hair loss. Further investigations are needed because there is a shortage of evidence on this novel diagnostic method.

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来源期刊
CiteScore
3.10
自引率
4.80%
发文量
0
期刊介绍: The aim of the International Journal of Endocrinology and Metabolism (IJEM) is to increase knowledge, stimulate research in the field of endocrinology, and promote better management of patients with endocrinological disorders. To achieve this goal, the journal publishes original research papers on human, animal and cell culture studies relevant to endocrinology.
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