肝上皮样血管内皮瘤:它的生长速度有多快,哪些发现可以防止诊断延误?-一份病例报告。

IF 3 4区 医学 Q1 Medicine Translational gastroenterology and hepatology Pub Date : 2023-01-01 DOI:10.21037/tgh-22-48
Michele Costa de Oliveira Ribeiro, Juliana Viana Baião Lemos, Marcelo Padovani de Toledo Moraes, Felipe Aguera Oliver, Matheus Alvarez, Giovanni Faria Silva, Xingshun Qi, Fernando Gomes Romeiro
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引用次数: 1

摘要

背景:肝上皮样血管内皮瘤(HEHE)是一种罕见的肿瘤疾病,早期表现多样,影像学征象不明确。诊断延迟可能导致转移性疾病,从而增加肿瘤负担并减少治疗选择。HEHE通常被认为是一种生长缓慢的肿瘤,但其生长速度报道很少,至今仍不清楚。病例描述:在本病例报告中,我们记录了一位年轻女性诊断为HEHE,她长期抱怨腹痛,体重减轻和腹胀。组织学研究中观察到的典型表现在组织学分析中未能及时发现,即使在两次腹腔镜指导下的肝脏活检后也未能及时发现,导致诊断延迟至肝外肿瘤扩散。本文介绍了计算机断层扫描、磁共振成像和组织学研究的结果。在特定的时间跨度内,结节的合并和巨大肿块的上升占据了肝脏的大部分,被记录和量化。与以往的报道相反,结果表明肝脏HEHE可以快速生长,因此需要早期诊断,从而避免本文所述的并发症。结论:通过放射学和组织学成像观察到的结果可以避免诊断延误,并对其进行了描述和讨论,表明HEHE的上升速度比以前文献记载的要快。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Hepatic epithelioid hemangioendothelioma: how fast does it grow and which findings could have prevented diagnostic delay?-a case report.

Background: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplastic disease of varied presentation and unspecific radiological signs in the early stages. The diagnostic delay can lead to metastatic disease, thus increasing the tumor burden and reducing the treatment options. HEHE is usually deemed a slow-growing tumor, but its speed of growth is poorly reported and still unknown.

Case description: In this case report, we documented a HEHE diagnosed in a young woman who had complaints of abdominal pain, weight loss and bloating for a long time. The typical findings observed in histological studies were not promptly recognized in the histological analyzes, even after two laparoscopic-guided liver biopsies, delaying the diagnosis until extrahepatic tumor spreading. Findings observed in computed tomography, magnetic resonance imaging and histological studies are presented. The coalescence of nodules and the rising of giant masses, occupying large parts of the liver in a specific time span, were registered and quantified. As opposed to prior reports, the results show that hepatic HEHE can grow rapidly, reinforcing the need of early diagnosis, thus avoiding the complications presented herein.

Conclusions: The findings observed via radiological and histological imaging that could have avoided the diagnosis delay are depicted and discussed, showing that HEHE can rise faster than previously documented.

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来源期刊
CiteScore
8.20
自引率
0.00%
发文量
1
期刊介绍: Translational Gastroenterology and Hepatology (Transl Gastroenterol Hepatol; TGH; Online ISSN 2415-1289) is an open-access, peer-reviewed online journal that focuses on cutting-edge findings in the field of translational research in gastroenterology and hepatology and provides current and practical information on diagnosis, prevention and clinical investigations of gastrointestinal, pancreas, gallbladder and hepatic diseases. Specific areas of interest include, but not limited to, multimodality therapy, biomarkers, imaging, biology, pathology, and technical advances related to gastrointestinal and hepatic diseases. Contributions pertinent to gastroenterology and hepatology are also included from related fields such as nutrition, surgery, public health, human genetics, basic sciences, education, sociology, and nursing.
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