不同年龄和危险人群新冠肺炎致肝损伤情况述评

Öner Özdemir, Hacer Efnan Melek Arsoy
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引用次数: 0

摘要

2019年底,中国湖北省武汉市出现了一种新型冠状病毒——严重急性呼吸系统综合征。第一次发病被描述为肺炎病例。2019冠状病毒病(COVID-19)的进展主要表现为症状,从轻度上呼吸道感染到严重肺炎、急性呼吸窘迫综合征和死亡。这种病毒可影响包括胃肠道在内的所有系统,确定其作用机制对于预测疾病进展和管理其治疗至关重要。重要的是要证明COVID-19在以前没有已知慢性或全身性疾病的患者中的作用机制。虽然目前还没有针对这种病毒的特异性治疗方法,但各种算法已经被创造出来。由于应用的算法,一些患者对治疗的反应是满意的,而一些患者出现了意想不到的副作用。它有助于澄清发生的不良反应是由于疾病的影响还是治疗中使用的药物的副作用。目前,人们对COVID-19与肝组织的相互作用越来越感兴趣。因此,我们想讨论当前文献中肝损伤/功能障碍的细节。
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Commentary on COVID-19-induced liver injury in various age and risk groups.

Towards the end of 2019, a new type of coronavirus, severe acute respiratory syndrome, emerged in the city of Wuhan in China's Hubei Province. The first occurrence was described as a case of pneumonia. Coronavirus disease 2019 (COVID-19) can progress primarily with symptoms varying from a mild upper respiratory tract infection to severe pneumonia, acute respiratory distress syndrome, and death. Determining the mechanisms of action of this virus, which can affect all systems including gastrointestinal, is vital for predicting the progression of the disease and managing its treatment. It is important to demonstrate the mechanisms of action of COVID-19 in patients without a previously known chronic or systemic disease. Although there is still no specific treatment for the virus, various algorithms have been created. As a result of the applied algorithms, the response to the treatment was satisfactory in some patients, while unexpected side effects occurred in some patients. It helps to clarify whether the unwanted effects that occur are due to the effect of the disease or the side effects of the drugs used in the treatment. There is currently increasing interest in COVID-19 interaction with liver tissue. Therefore, we would like to discuss the details of liver injury/dysfunction in the current literature.

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