植物雌激素对生殖器官健康的影响

IF 6.9 3区 医学 Q1 CHEMISTRY, MEDICINAL Archives of Pharmacal Research Pub Date : 2022-11-28 DOI:10.1007/s12272-022-01417-y
S. Swathi Krishna, Beena Briget Kuriakose, P. K. Lakshmi
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引用次数: 8

摘要

植物雌激素是从植物中提取的非甾体多酚类化合物,具有与人类雌激素相似的生物学特性。它们的生物活性基于核心环系统,是由它们与雌激素的结构相似性引起的。类黄酮、库米斯坦、木脂素和二苯乙烯是它们可以分为的四大类。它们在结构和功能上与卵巢和胎盘雌激素相关,而卵巢和胎盘雌激素在女性生殖过程中是必不可少的。植物雌激素存在于许多膳食补充剂中,并作为合成激素的替代品在激素替代疗法中得到应用。此外,它们对骨质疏松症、心脏病、乳腺癌和前列腺癌都有健康益处。人们对使用植物雌激素作为营养保健品的预防药物越来越感兴趣。这篇文献提供了关于植物雌激素在生殖系统中的类型、来源和生物作用的全面信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Effects of phytoestrogens on reproductive organ health

Phytoestrogens are non-steroidal, polyphenolic compounds that are derived from plants and have biological properties similar to those of human estrogens. Their bioactivity, which is based on the core ring system, is caused by their structural resemblance to estrogen. Flavonoids, coumestans, lignans, and stilbenes are the four major categories into which they can be divided. They are structurally and functionally related to ovarian and placental estrogens, which are essential in female reproductive processes. Phytoestrogens are present in numerous dietary supplements and find application in hormone replacement therapy as an alternative to synthetic hormones. In addition, they provide health benefits for osteoporosis, heart disease, breast cancer, and prostate cancer. There is a growing interest in using phytoestrogen as preventative medicine in the form of nutraceuticals. This literature provides comprehensive information about the types, sources, and biological actions of phytoestrogens in the reproductive system.

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来源期刊
CiteScore
13.40
自引率
9.00%
发文量
48
审稿时长
3.3 months
期刊介绍: Archives of Pharmacal Research is the official journal of the Pharmaceutical Society of Korea and has been published since 1976. Archives of Pharmacal Research is an interdisciplinary journal devoted to the publication of original scientific research papers and reviews in the fields of drug discovery, drug development, and drug actions with a view to providing fundamental and novel information on drugs and drug candidates.
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