色氨酸及其代谢物色谱快速灵敏分析研究进展

Ibolya Molnár-Perl
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引用次数: 2

摘要

最新分析方法的发展现状,一方面应用于蛋白质水解产物中色氨酸的可靠和可重复的定量,另一方面适用于源自吲哚和犬尿氨酸途径的生物基质中色氨酸及其代谢物的鉴定和定量。分析过程根据其优点和缺点(选择性、灵敏度、时间/成本要求等)进行评价和批评。
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Advancements in the rapid and sensitive analyses of tryptophan and its metabolites, by chromatography

The state of the art of recent analytical method developments, applied on the one part on the reliable and reproducible quantitation of tryptophan in protein hydrolyzates, on the other part proper for the identification and quantification of tryptophan and its metabolites in biological matrices originating both from the indolyl- and kynurenine pathways. Analytical processes are evaluated and criticized on the basis of their advantages and shortcomings (selectivity, sensitivity, time/cost requirement, etc).

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