亚洲局部晚期胃癌患者的新辅助化疗。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2023-01-01 DOI:10.5230/jgc.2023.23.e12
Xie Tong, Peng Zhi, Shen Lin
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引用次数: 0

摘要

手术是目前胃癌唯一的治疗手段,改善局部进展期胃癌的预后是提高胃癌生存效益的关键因素之一。MAGIC研究是欧洲国家首次证明新辅助化疗(NAC)疗效的研究。近年来,一些临床试验为NAC在亚洲局部晚期胃癌患者中的应用提供了证据。然而,临床实践指南在亚洲和非亚洲人群之间有所不同。亚洲患者NAC的最佳方案、适当的目标人群和预后预测因素仍在研究中。在此,我们总结了目前NAC在亚洲胃癌患者中的应用进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Neoadjuvant Chemotherapy in Asian Patients With Locally Advanced Gastric Cancer.

Presently, surgery is the only treatment approach for gastric cancer and improving the prognosis of locally advanced gastric cancer is one of the key factors in promoting gastric cancer survival benefit. The MAGIC study was the first to demonstrate the efficacy of neoadjuvant chemotherapy (NAC) in European countries. In recent years, several clinical trials have provided evidence for the use of NAC in Asian patients with locally advanced gastric cancer. However, clinical practice guidelines vary between Asian and non-Asian populations. Optimal NAC regimens, proper target populations, and predictors of NAC outcomes in Asian patients are still under investigation. Herein, we summarized the current progress in the administration of NAC in Asian patients with gastric cancer.

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CiteScore
7.20
自引率
4.30%
发文量
567
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