皮肤淋巴瘤的无创皮肤影像学研究。

IF 8.6 1区 医学 Q1 DERMATOLOGY American Journal of Clinical Dermatology Pub Date : 2023-11-14 DOI:10.1007/s40257-023-00824-1
Eyal Taleb, Oriol Yélamos, Marco Ardigo, Rachel E. Christensen, Shamir Geller
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引用次数: 0

摘要

皮肤淋巴瘤的诊断具有挑战性,需要使用免疫组织化学和分子研究对皮肤组织进行组织学和免疫表型分析。近年来,非侵入性成像技术的作用已被描述为皮肤淋巴瘤病变临床评估的一部分。影像学手段,如皮肤镜、反射共聚焦显微镜(RCM)和高频超声(HFUS)已被证明在提高临床对皮肤淋巴瘤的怀疑,以及在区分皮肤淋巴瘤与炎性皮肤病(如狼疮、牛皮癣或湿疹)方面非常有价值。这些非侵入性方法可用于指导临床医生到最佳的活检部位,以最大限度地提高组织病理学结果,并尽量减少假阴性。这些方法在监测治疗反应方面也有潜在的作用。在这篇综述中,我们对皮肤t细胞淋巴瘤(CTCL)和b细胞淋巴瘤(CBCL)的皮肤镜成像、RCM和HFUS特征进行了简要总结。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Non-invasive Skin Imaging in Cutaneous Lymphomas

The diagnosis of cutaneous lymphomas is challenging and requires skin tissue for histology and immunophenotyping using immunohistochemistry and molecular studies. In recent years, the role of non-invasive imaging techniques has been described as part of the clinical assessment of cutaneous lymphoma lesions. Imaging modalities such as dermoscopy, reflectance confocal microscopy (RCM), and high frequency ultrasound (HFUS) have been shown to be very valuable in raising the clinical suspicion for lymphomas of the skin, and in distinguishing cutaneous lymphomas from inflammatory dermatoses such as lupus, psoriasis, or eczema. These non-invasive methods can be used to direct the clinician to the optimal biopsy site to maximize the histopathological results and minimize false negatives. These methods also have a potential place in monitoring treatment response. In this review we present a concise summary of the dermoscopic imaging, RCM, and HFUS features seen in cutaneous T-cell lymphomas (CTCL) and B-cell lymphomas (CBCL).

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来源期刊
CiteScore
15.20
自引率
2.70%
发文量
84
审稿时长
>12 weeks
期刊介绍: The American Journal of Clinical Dermatology is dedicated to evidence-based therapy and effective patient management in dermatology. It publishes critical review articles and clinically focused original research covering comprehensive aspects of dermatological conditions. The journal enhances visibility and educational value through features like Key Points summaries, plain language summaries, and various digital elements, ensuring accessibility and depth for a diverse readership.
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