[冰岛孕妇头发中的汞含量]。

IF 0.4 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Laeknabladid Pub Date : 2023-03-01 DOI:10.17992/lbl.2023.03.733
Edda Dufthaksdottir, Eva Jacobsen, Asa Valgerdur Eiriksdottir, Ola Kally Magnusdottir, Kristin Olafsdottir, Thorhallur Ingi Halldorsson
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引用次数: 0

摘要

导言:为了限制接触甲基汞,一些国家对孕妇的鱼类摄入量提出了具体建议,并通过定期人体生物监测来衡量遵守情况。尽管冰岛的鱼类摄入量相对较高,但人类对汞的生物监测数据却很少。材料和方法:我们测量了2021年从雷克雅未克首都地区招募的120名孕妇头发中的汞含量。在招募时,记录了过去四个月的鱼类摄入量信息。将头发汞浓度与现有的基于健康的指导值进行了比较,并探讨了与鱼类摄入量的关系。结果:毛发中汞浓度均值(标准差)为0.48 μg/g(0.33)。所有参与者头发中的浓度均低于1.8 μg/g,这与欧洲食品安全局设定的每日可耐受摄入量的头发值相对应,而5%的浓度高于1.1 μg/g,这与美国环保署参考剂量的头发值相对应。头发中的平均汞浓度呈剂量依赖性增加(p表示趋势)。结论:我们的研究结果表明,接触量通常低于欧洲食品安全局规定的每日可耐受摄入量,但在一些妇女中可能超过美国环保署规定的参考剂量。
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[Levels of mercury in hair among pregnant women in Iceland].

Introduction: To limit exposure to methylmercury several countries have implimented specific advice on fish intake to pregnant women as well a measuring compliance through regular human biomonitoring. Despite fish intake being relatively high in Iceland, human biomonitoring data on mercury is scarce.

Materials and mehods: We measured mercury in hair from 120 pregnant women recruited in 2021 from the the Reykjavik Capital area. At recruitment, information on fish intake during the past four months was recorded. Hair mercury concentrations were compared to existing health based guidance values and associatons with fish intake was explored.

Results: Mean (standard deviation) mercury concentration in hair was 0.48 μg/g (0.33). All participants had concentrations in hair below 1.8 μg/g, which corresponds to the hair value that the tolerable daily intake set by the European Food Safety Authority is derived from, while 5% had concentrations above 1.1 μg/g, which corresponds to the hair value that the US-EPA reference dose is derived from. Mean mercury concentrations in hair increased in a dose dependent manner (p for trend p<0.001) from 0.25 μg/g among women who consumed fish ≤ 3/month (n=24) and up to 0.80 mg/g among those consuming fish 3-4/ week (n=16). The few (n=3) women who reported to have eaten shark (p<1/month) were all at the higher end of the exposure distribution.

Conclusion: Our results suggest that exposure is generally below the tolerable daily intake set by EFSA but may in some women exceed the reference dose established by the US-EPA.

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来源期刊
Laeknabladid
Laeknabladid MEDICINE, GENERAL & INTERNAL-
CiteScore
0.50
自引率
25.00%
发文量
63
审稿时长
>12 weeks
期刊介绍: Læknablaðið er fræðirit sem birtir vísinda og yfirlitsgreinar og annað efni sem byggir á rannsóknum innan læknisfræði eða skyldra greina. Læknablaðið er gefið út af Læknafélagi Íslands. Blaðið er sent til allra félagsmanna. Það var fyrst gefið út árið 1904 en hefur komið samfellt út frá árinu 1915. Blaðið kemur út 11 sinnum á ári og er prentað í 2000 eintökum. Allt efni Læknablaðsins frá árinu 2000 er aðgengilegt á heimasíðu blaðsins á laeknabladid.is og er aðgangur endurgjaldslaus og öllum opinn.
期刊最新文献
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