Samiullah Arshad, Rachel D Cutting, Daniel J Stephens, Ythan H Goldberg, Claudius Mahr, Mahender Vyasabattu, Ahmed H Abdelfattah, Gaurang N Vaidya
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Left ventricular assist devices (LVADs) have revolutionized the management of patients with advanced heart failure refractory to medical therapy. Current indications of LVADs include Bridge to Transplantation (BTT), Destination Therapy (DT) for long-term use, Bridge to the Decision (BTD) used as a temporary measure, and lastly Bridge to Recovery (BTR). Here, we briefly review the clinical evidence and the molecular mechanisms behind myocardial recovery following LVAD placement. We also share institutional protocols used at 2 major medical centers in the USA.
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