{"title":"小鼠尿液中γ -和β -六六六酚的代谢物:氯酚偶联物。","authors":"N Kurihara","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Metabolites produced from gamma- and beta-BHC in the mouse urine were purified and characterized. Most metabolites from both isomers were not extractable by non-polar organic solvents and were conjugates such as sulfates and glucuronides. After hydrolysis with an appropriate enzyme, the conjugates gave chlorophenols, among which 2,4,6-trichlorophenol existed most abundantly (total, about 25% in the urine metabolites). 2,4-Dichlorophenol also constituted a significant portion.</p>","PeriodicalId":75827,"journal":{"name":"Environmental quality and safety","volume":"4 ","pages":"56-73"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Urinary metabolites from gamma- and beta-BHC in the mouse: chlorophenol conjugates.\",\"authors\":\"N Kurihara\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Metabolites produced from gamma- and beta-BHC in the mouse urine were purified and characterized. Most metabolites from both isomers were not extractable by non-polar organic solvents and were conjugates such as sulfates and glucuronides. After hydrolysis with an appropriate enzyme, the conjugates gave chlorophenols, among which 2,4,6-trichlorophenol existed most abundantly (total, about 25% in the urine metabolites). 2,4-Dichlorophenol also constituted a significant portion.</p>\",\"PeriodicalId\":75827,\"journal\":{\"name\":\"Environmental quality and safety\",\"volume\":\"4 \",\"pages\":\"56-73\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1975-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental quality and safety\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental quality and safety","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Urinary metabolites from gamma- and beta-BHC in the mouse: chlorophenol conjugates.
Metabolites produced from gamma- and beta-BHC in the mouse urine were purified and characterized. Most metabolites from both isomers were not extractable by non-polar organic solvents and were conjugates such as sulfates and glucuronides. After hydrolysis with an appropriate enzyme, the conjugates gave chlorophenols, among which 2,4,6-trichlorophenol existed most abundantly (total, about 25% in the urine metabolites). 2,4-Dichlorophenol also constituted a significant portion.
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