[不同麻黄碱异构体对离体灌注兔心脏去甲肾上腺素摄取的构效关系]。

Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles Pub Date : 1978-11-13

P H Chanh, A P Chanh, M C Azum-Gelade, A Taudou, M N van Thoai

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引用次数: 0

摘要

(-)麻黄碱，(+)麻黄碱，(-)psi麻黄碱和(+)psi麻黄碱抑制离体兔心脏神经元和神经元外对去甲肾上腺素的摄取。(-)麻黄碱是抑制神经元和神经元外摄取的最活跃的异构体。当应用于一种或另一种摄取时，其他三种异构体的相对抑制电位是不相同的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Structure-activity relationship of various ephedrine isomers on noradrenaline uptake by the isolated perfused rabbit heart].

(-)Ephedrine, (+) Ephedrine, (-) psi ephedrine and (+) psi ephedrine inhibit both the neuronal and extraneuronal uptakes of noradrenaline in isolated Rabbit heart. (-) ephedrine is the most active isomer for the inhibition of both neuronal and extraneuronal uptakes. The relative inhibition potential of the three other isomers is not the same when applied to one or other uptake.

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来源期刊

Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles

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