抗癫痫药物与癫痫发作类型的关系

M. Deepan, R. PraveenKumar
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引用次数: 1

摘要

背景:癫痫发作是儿童最常见的疾病之一,抗癫痫药物因癫痫发作的类型而异。方法:对50例1 ~ 12岁需要抗癫痫药物治疗癫痫发作的儿童进行分析比较。癫痫发作模仿障碍被排除在本研究之外。结果:50例患者中,丙戊酸钠以全局性癫痫发作为主,其次为丙戊酸钠与苯妥英联合用药,其次为苯妥英与左乙曲西坦联合用药。对于局灶性癫痫,主要使用卡马西平。讨论:基于病史和癫痫发作类型的初步评估对儿科医生评估使用的抗癫痫药物类型很重要。结论:丙戊酸钠和苯妥英用于全面性癫痫发作,卡马西平用于局灶性癫痫发作。
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Relationship between antiepileptic medications and type of seizures
Background: Seizure is one of the most common disorder in children and anti epileptics vary depending on the type of seizures occurring. Methods: In total 50 children of age between 1-12 years requiring anti epileptics for seizure are taken into consideration and compared. Seizure mimicking disorder were excluded from this study. Results: Among the 50 patients, valproate was predominantly used for generalized seizures followed by combination therapy of valproate and phenytoin followed by phenytoin and Levetiracetam. For focal sezuires, carbamazepine was used predominantly. Discussion: The initial evaluation based on history and examination for the type of seizures is important for pediatrician to assess the type of anti epileptic used. Conclusion: Valproate and phenytoin are mostly used for generalized type of seizures while carbamazepine is used for focal type of seizures.
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