基于深度复杂神经网络的超声颈动脉血流速度测量

Jian Lei, Xun Lang, Bingbing He, Songhua Liu, Hao Tan, Yufeng Zhang
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引用次数: 1

摘要

颈动脉血流的精确测量对于研究血栓形成和早期颈动脉粥样硬化斑块至关重要。然而,传统的非参数方法对低速血流的检测能力较弱,存在测量偏差大、算法运行时间长等问题。基于以上现状,本文提出了一种基于深度复杂卷积神经网络(DCCNN)的颈动脉血流速度测量方法。DCCNN基于监督学习,将回波信号送入复卷积层,以抑制杂波信号。然后,将复卷积层的输出经过复全连通层的处理来估计血流速度。通过仿真和健康志愿者的体内数据验证了该方法的有效性。与高通滤波和奇异值分解等典型测速方法相比,该方法得到的测速结果的归一化均方根误差(NRMSE)分别降低了47.20%和45.45%,拟合优度分别提高了5.64%和3.36%。此外,DCCNN的运行时间分别缩短了82.10%和21.11%。结果表明,该方法具有较高的测速精度和良好的实时性,是一种很有前途的血流速度测量工具。
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Ultrasonic Carotid Blood Flow Velocimetry Based on Deep Complex Neural Network
Precise measurement of carotid artery blood flow is of vital importance for studying thrombosis and early carotid atherosclerotic plaque. However, the traditional non-parametric methods are limited by the weak detection ability to low-velocity blood flow, and show problems including the large measurement deviation and long algorithm running time. Motivated by the above status quo, a novel method based on deep complex convolutional neural network (DCCNN) is proposed for carotid blood flow velocimetry. Based on supervised learning, DCCNN feeds the echo signals into complex convolutional layers for the purpose of rejecting clutter signals. Then, the outputs of complex convolutional layers are processed by the complex fully connected layers to estimate the blood flow velocity. The effectiveness of the proposed method is verified by simulation as well as in vivo data of healthy volunteers. Compared with typical velocimetry methods such as the high-pass filter and singular value decomposition, the normalized root mean square error (NRMSE) of the velocimetry result obtained from the proposed method is reduced by 47.20%) and 45.45%, and the goodness-of-fit is improved by 5.64%, 3.36%, respectively. In addition, the running time of DCCNN is reduced by 82.10% and 21.11%, respectively. Such results show that the proposed method is a promising tool for blood flow velocity measurement due to its higher velocity measurement accuracy and good real-time performance.
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