维生素B-6(吡哆醇)

Laboratory Tests for the Assessment of Nutritional Status Pub Date : 2018-12-19 DOI:10.1201/9780203749647-5

Howerde E. Sauberlich

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引用次数: 3

摘要

除吡啶酸[2]和吡啶醇外，其它形式均可相互转化。吸收的吡哆沙胺经吡哆醛激酶转化为PMP，再经吡哆沙胺-磷酸转氨酶或吡哆沙醇5′-磷酸氧化酶转化为PLP，并催化PNP转化为PLP。吡哆醇5′-磷酸氧化酶依赖于黄素单核苷酸(FMN)作为辅助因子，而黄素单核苷酸是由核黄素(维生素B2)产生的，即在这一生化途径中，没有维生素B2，膳食中的维生素B6就不能使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vitamin B-6 (Pyridoxine)

All forms except pyridoxic acid[2] and pyritinol can be interconverted. Absorbed pyridoxamine is converted to PMP by pyridoxal kinase, which is further converted to PLP by pyridoxamine-phosphate transaminase or pyridoxine 5′-phosphate oxidase which also catalyzes the conversion of PNP to PLP. Pyridoxine 5′-phosphate oxidase is dependent on flavin mononucleotide (FMN) as a cofactor which is produced from riboflavin (vitamin B2) i.e. in this biochemical pathway, dietary vitamin B6 cannot be used without vitamin B2.

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