P Jollès, D Migliore-Samour, R Maral, F Floc'h, G H Werner
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Low molecular weight water-soluble peptidoglycans as adjuvants and immunostimulants.
The tetrasaccharide-heptapeptide (TH), when injected with mineral oil, exerted a strong adjuvant effect. It stimulated B and T cells, but did not increase the phagocytic activity of the reticulo-endothelial system. While BCG exerted significant preventive effect on the growth of sarcoma 180, leucosarcomatosis an EHRLICH ascitic tumor, TH, at the doses used, was devoid of such activity.
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