低剂量OTA暴露对断奶仔猪肠道微生物群的影响

I. Grosu, A. Cișmileanu, D. Marin, I. Țăranu
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引用次数: 2

摘要

饲料污染是养猪业关注的主要问题。真菌毒素,特别是赭曲霉毒素a对猪的整体健康和发育的有害影响日益受到关注。然而,对胃肠道微生物群的有害影响尚未得到充分研究,特别是在低剂量暴露下。目前的研究建议调查亚慢性剂量的OTA对定植在猪肠道的一些重要细菌种群的影响,并评估对短链脂肪酸生产的影响。细菌种群的变化不仅影响猪的免疫系统,而且影响真菌中毒的发展。本文重点研究了0.05mg/kg的OTA饲料对大肠菌群和与之相关的短链脂肪酸产量的影响。
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The effects of a low dose OTA exposure on weanling piglet gut microbiota
Abstract Feed contamination is a major concern to the pig farming industry. There is a growing concern towards the harmful effects that mycotoxins and especially ochratoxin A have on the overall health and development of pigs. However the deleterious effects on the gastro-intestinal microbiota has not been studied thoroughly, especially at a low dose exposure. The current study proposed to investigate the effect of a sub-chronic dose of OTA on some of the important bacterial populations colonizing the pig gut as well as assessing the impact on SCFA production. The changes induced in bacterial populations not only affect the immune system of the pig but also influence the development of the mycotoxicosis. This paper highlights the impact of 0.05mg/kg feed of OTA on the large intestine microbiota and on the SCFA production associated with it.
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