Thieno [2,3 -d]嘧啶-4-one的光谱和生物学分析

R. ., Dharmendra Kumar, Prof Vikas Kumar, Leeladhar Singh
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引用次数: 0

摘要

以2-氨基-3-碳乙氧基噻吩和甲酰胺为原料合成了噻吩[2,3-d]嘧啶-4-酮,并利用FTIR、UV-Vis和1H-NMR等方法确定了其结构。合成的化合物对大肠杆菌、枯草芽孢杆菌和金黄色葡萄球菌以及白色念珠菌、黑曲霉和克鲁氏念珠菌的抑菌活性进行了测试。
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Spectral and Biological analysis of Thieno [2, 3-d] pyrimidin-4-one
Thieno [2,3-d] pyrimidin-4-one is synthesized by 2-amino-3-carboethoxythiophene and fomamide and its structure was also established using FTIR, UV-Vis and 1H-NMR spectroscopic method. The synthesized compound was also tested for antimicrobial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus and fungus Candida albican, Aspergillus niger and Candida krusei.
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