新冠肺炎后毛霉菌病患者鼻窦、眶内和颅内延伸的影像学评价

T. Kalekar, V. Rangankar, Pooja Karanjule, Radhika K. Jaipuria, Sahil Kathuria, Neeraj Patil, Giri Nk
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摘要

背景:毛霉病是一种致命的进行性疾病,影响后covid状态的免疫功能低下患者。计算机断层扫描和磁共振成像的放射学评估有助于确定疾病的严重程度和范围。目的:本研究的目的是利用计算机断层扫描和磁共振成像等放射学检查评估covid后患者的毛霉菌病,并研究糖尿病患者和使用类固醇/免疫抑制剂的患者的疾病程度。方法:于2021年3月至6月在浦那Pimpri Patil医院和医学院进行了一项前瞻性观察研究。所有出现毛霉病的患者要么是COVID-19阳性,要么是从COVID-19感染中恢复的。对这些患者进行了计算机断层扫描和磁共振成像。结果:糖尿病状态与受累程度、类固醇/免疫抑制剂使用与受累程度的相关性有统计学意义,p值<0.001。结论:新型冠状病毒感染后和糖尿病患者在治疗期间使用类固醇治疗可能会增加发生毛霉病等机会性感染的风险。新型冠状病毒相关毛霉病的计算机断层扫描和磁共振成像
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RADIOLOGICAL EVALUATION OF SINONASAL, INTRAORBITAL AND INTRACRANIAL EXTENSION OF MUCORMYCOSIS IN POSTCOVID PATIENTS
Background: Mucormycosis is a fatal and progressive condition that affects immunocompromised patients in the post-COVID state. Radiological assessment by computed tomography and magnetic resonance imaging is useful to determine the severity and extent of the disease. Objective: The objective of this research is to evaluate mucormycosis in post-COVID patients using radiological investigations like computed tomography and magnetic resonance imaging and also to study the extent of disease in patients with diabetes and with steroid/ immunosuppressant use. Methods: A prospective observational study was undertaken at Dr. D. Y. Patil Hospital and Medical College, Pimpri Pune from March-June 2021. All patients who presented with mucormycosis were either COVID-19 positive or recovered from COVID-19 infection. Computed tomography and magnetic resonance imaging were performed in these patients. Results: The association between the status of diabetes mellitus and extent of involvement, steroids/immunosuppressant use and extent of involvement was statistically significant with a p value of <0.001. Conclusion: Patients with post COVID-19 status and diabetic status with steroid therapy during the treatment of COVID-19 may increase the risk of developingopportunistic infections like mucormycosis. Post COVID-19 related mucormycosis on computed tomography and magnetic resonance imaging
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