Esra Özkan Kaya, S. Çalışkan
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摘要

口腔由不同组织学结构和功能的组织组成,可发生良性、癌前和恶性病变。对于有恶性肿瘤潜力的病变;术语为癌前、潜在恶性、癌前、上皮内瘤变。恶性病变可能起源于癌前病变。癌前病变比正常组织更容易转变为恶性特征。而对于处于生长发育阶段的儿童,诊断准确,恶性转化的风险降低,治疗简单。口腔粘膜癌前病变的病因尚不完全清楚,但主要因素可能是上瘾的习惯,如吸烟、饮酒或咀嚼槟榔。这些有害习惯在儿童中急剧增加,尤其是在幼儿时期,并造成公共卫生问题。口腔癌和癌前病变在儿童时期很少见。据指出,营养缺乏、遗传易感性和感染人乳头瘤病毒的人是患癌前病变的高风险群体。牙医在学龄前儿童口腔癌前/恶性病变的早期诊断中发挥着重要作用,可以在识别高危患者方面做出贡献。本文综述的目的是提供关于儿童癌前病变的诊断、临床特征、病因和治疗方法的最新信息。
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Çocuklarda Görülen Ağız İçi Premalign Lezyonlar
The oral cavity consists of tissues with different histological structure and function, and benign, premalignant and malignant lesions may occur. For lesions with malignancy potential; the terms premalignant, potential malignant, precancerous, intraepithelial neoplasia are used. Malignant lesions may originate from premalignant lesions. Premalignant lesions are morelikely to turnin to malignant characters than normal tissues. However, when diagnose dearly, the risk of malignant transformation is reduced and treatment is simpler for children which in growth and development process. The etiological factors of the precancerous lesions of the oral mucosa are not fully understood, but the main factors may be addictive habits such as smoking, alcohol consumption, or arecanut chewing. These harmful habits increase dramatically in children, especially at an early age, and create a public health problem. Oral cancers and precancerous lesions are rarely encountered in childhood. It is stated that people with nutritional deficiencies, genetic predisposition and people with human papillomavirus constitute a high risk group for premalignant lesions. Dentists play an important role in the early diagnosis of premalignant / malignant lesions of the oral region in preschool children and can make a contribution in identifying high-risk patients. Aim of this review was to provide recentin formation about the diagnosis, clinical features, etiology and treatment approach of premalignant lesions in children.
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