多发性骨髓瘤中的刺猬信号通路

Annals of Research in Oncology Pub Date : 2022-05-01 DOI:10.48286/aro.2022.47

I. Dulcamare, S. Giallongo, N. Vicario, G. Scandura, A. Barbato, E. La Spina, L. Longhitano, D. Cambria, D. Tibullo, T. Zuppelli, D. Lo Furno, R. Parenti, G. Li Volti, G. Palumbo, F. Di Raimondo, A. Romano, C. Giallongo

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摘要

多发性骨髓瘤是一种以骨髓恶性浆细胞不受控制的增殖为特征的血液系统疾病。恶性细胞的定位和存活依赖于骨髓生态位，而骨髓生态位又由MM细胞和间充质间质细胞(MSCs)之间的相互作用决定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Hedgehog signaling pathways in multiple myeloma

Multiple myeloma (MM) is a hematological disease characterized by the uncontrolled proliferation of bone marrow malignant plasma cells. Localization and survival of malignant cells relies on bone marrow niche, in turn determined by the interaction between MM cells and mesenchymal stromal cells (MSCs)

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Annals of Research in Oncology

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