Xiaotian Du, Caroline Ladegard, Xiao Ma, Xuanhong Cheng, J. Hwang
{"title":"900 ~ 40 GHz活细胞中细胞核大小的宽带电传感","authors":"Xiaotian Du, Caroline Ladegard, Xiao Ma, Xuanhong Cheng, J. Hwang","doi":"10.1109/IMBIoC47321.2020.9385023","DOIUrl":null,"url":null,"abstract":"Live Jurkat cells were trapped by dielectrophoresis on a coplanar waveguide and the resulted changes in its reflection and transmission coefficients were measured from 900 Hz to 40 GHz. The measurement confirms that the decrease of nucleus size in a cell increases its impacts on both the reflection and transmission coefficients. Being fast, compact and label free, broadband electrical sensing may be used to detect other changes of the nucleus morphology and DNA content, which could be useful for cancer diagnosis.","PeriodicalId":297049,"journal":{"name":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Broadband Electrical Sensing of Nucleus Size in a Live Cell From 900 Hz to 40 GHz\",\"authors\":\"Xiaotian Du, Caroline Ladegard, Xiao Ma, Xuanhong Cheng, J. Hwang\",\"doi\":\"10.1109/IMBIoC47321.2020.9385023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Live Jurkat cells were trapped by dielectrophoresis on a coplanar waveguide and the resulted changes in its reflection and transmission coefficients were measured from 900 Hz to 40 GHz. The measurement confirms that the decrease of nucleus size in a cell increases its impacts on both the reflection and transmission coefficients. Being fast, compact and label free, broadband electrical sensing may be used to detect other changes of the nucleus morphology and DNA content, which could be useful for cancer diagnosis.\",\"PeriodicalId\":297049,\"journal\":{\"name\":\"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)\",\"volume\":\"28 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IMBIoC47321.2020.9385023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2020 IEEE MTT-S International Microwave Biomedical Conference (IMBioC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IMBIoC47321.2020.9385023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Broadband Electrical Sensing of Nucleus Size in a Live Cell From 900 Hz to 40 GHz
Live Jurkat cells were trapped by dielectrophoresis on a coplanar waveguide and the resulted changes in its reflection and transmission coefficients were measured from 900 Hz to 40 GHz. The measurement confirms that the decrease of nucleus size in a cell increases its impacts on both the reflection and transmission coefficients. Being fast, compact and label free, broadband electrical sensing may be used to detect other changes of the nucleus morphology and DNA content, which could be useful for cancer diagnosis.
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