可吸入纳米颗粒的发展

Leticia Ely, R. Löbenberg, Zhao-quan Wang, Yu Zhang, W. Finlay, W. Roa, Jeffrey O. H. Sham
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引用次数: 3

摘要

这项研究的目的是开发用于肺输送的纳米颗粒。采用喷雾干燥和新型喷雾冷冻干燥技术将纳米颗粒掺入载体颗粒中。所制备的载体颗粒具有适合肺输送的大小。这项新技术对局部药物靶向和基于纳米颗粒的药物递送系统的肺部递送具有重要意义。
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Development of Inhalable Nanoparticles
The aim of this study was to develop nanoparticles for lung delivery. Nanoparticles were incorporated into carrier particles using spray drying and a new spray-freeze drying technology. The carrier particles were manufactured with the appropriate size for pulmonary delivery. The new technology has important implications for local drug targeting and drug delivery of nanoparticle based delivery systems to the lungs.
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