{"title":"ADM (Dermacell)治疗手部肥厚性瘢痕(HSs)后挛缩性瘢痕","authors":"Spyridon Maragkos, Giampietro Bertasi, Mariana Peroni","doi":"10.53294/ijfstr.2022.3.2.0052","DOIUrl":null,"url":null,"abstract":"Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.","PeriodicalId":199114,"journal":{"name":"International Journal of Frontiers in Science and Technology Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Treatment of retractile scar after a hypetrophic scar (HSs) in the hand with ADM (Dermacell)\",\"authors\":\"Spyridon Maragkos, Giampietro Bertasi, Mariana Peroni\",\"doi\":\"10.53294/ijfstr.2022.3.2.0052\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.\",\"PeriodicalId\":199114,\"journal\":{\"name\":\"International Journal of Frontiers in Science and Technology Research\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Frontiers in Science and Technology Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53294/ijfstr.2022.3.2.0052\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Frontiers in Science and Technology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53294/ijfstr.2022.3.2.0052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Treatment of retractile scar after a hypetrophic scar (HSs) in the hand with ADM (Dermacell)
Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.