乙醇摄入对大鼠血浆生化及胰腺的影响。

Acta hepato-gastroenterologica Pub Date : 1979-08-01
S N Joffe, M M Ferrie, R O'Hare
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引用次数: 0

摘要

每天给予胃内乙醇4周可引起血浆淀粉酶和总蛋白的短暂升高,而总钙下降。4周胰腺光镜检查显示腺泡细胞脱颗粒和坏死,无炎症细胞浸润。胰腺的变化不太可能是人为的,而是由生化变化证实的酒精的直接毒性作用。
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The effect of ethanol ingestion on plasma biochemistry and the pancreas in the rat.

Intra-gastric ethanol given daily for 4 weeks caused transient elevations in plasma amylase and total protein with a fall in total calcium. Light microscopic examination of the pancreas at 4 weeks showed areas of acinar cell degranulation and necrosis without an inflammatory cell infiltrate. The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.

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Peroxidase activity in non-parenchymal cells isolated from rat liver: a cytochemical study. The analysis of stain loading tests for the assessment of the liver function. Parenteral nutrition. Semiquantitative determination of liver specific antigen in the urine or rats with toxic hepatic necrosis. Aortic stenosis--angiodysplasia of the caecum.
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