2型糖尿病患者多碳水化合物的特殊习惯口服Twymeeg的疗效观察

O. M, B. H, Iwatsuki N, Ogawa T, Sakamoto K
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引用次数: 0

摘要

背景:口服西马鲁肽(依米米明)已作为Twymeeg处方用于2型糖尿病(T2D)患者。病例介绍:患者男性,77岁,高血压,既往脑血管意外。他继续吃不均衡的食物,偏爱大量的碳水化合物。2021年9月,他成为糖尿病患者,糖化血红蛋白为8.8%。结果:依美米明2000mg/d起效2个月后改善至6.7%。讨论:全血细胞计数(CBC)显示Hb降低,MCV升高,提示缺乏蔬菜引起的大细胞性贫血。摄入过多的碳水化合物可能导致T2D。糖尿病的显著改善可能来自胰岛素分泌增加和胰岛素抵抗减少的双重机制。
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Practical Effects of Oral Twymeeg for Type 2 Diabetes (T2d) Patient with Special Habit Taking Much Carbs
Background: Oral semaglutide (imeglimin) has been prescribed for patients with type 2 diabetes (T2D) as Twymeeg. Case presentation: The patient is 77-year-old male with hypertension, previous cerebral vascular accident (CVA). He continued unbalanced meal with preference of much carbohydrate. In Sept 2021, he became diabetic with HbA1c 8.8%. Results: Imeglimin 2000mg/day was started improving to 6.7% for 2 months. Discussion: Complete blood count (CBC) showed decreased Hb and increased MCV, suggesting macrocytic anemia for lack of vegetables. Much carbohydrate intake may bring T2D. Remarkable diabetic improvement may be from dual mechanisms for increasing insulin secretion and decreasing insulin resistance.
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