草药提取物在根管消毒和去除涂抹层中的作用综述

Swapna Munaga, Kiran R Halkai, Abdul Kader Al Jarrah, Rajkiran Chitumalla, Rahul S Halkai, Sheeba Khan
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引用次数: 1

摘要

背景:根管治疗的成功与否取决于根管间隙的彻底清创和消毒。各种化学品已用于运河消毒。然而,为了克服大多数传统运河消毒剂的副作用、毒性问题和微生物耐药性,需要替代药剂。许多草药产品已被研究和推荐用于管道消毒。本文综述了中药提取物在肛管消毒中作为冲洗剂、肛管内药物的作用及其去除脏污层的效果。结果:通过搜索以下电子数据库确定研究:PubMed, Science direct, Scopus和Google Scholar。检索关键词:根管消毒用中药制剂/产品、粪肠球菌、牙髓学、涂片层、生物膜、中药提取物和抗菌活性。回顾了过去30年(1990年至2020年6月)的文献。结果表明,一些体外研究报告了草药提取物对根管消毒的有效抗菌作用,然而,很少有体内或临床研究报告确定这些药物用于根管治疗。结论:中药制剂可有效地用于肛管消毒。然而,需要进一步的长期、体外、临床、生物相容性研究和临床试验来确定这些产品在牙髓学中的应用。草药提取物因其独特的性质,可作为现有根管消毒剂的替代品。因此,通过预防根管失败、持续感染和再感染来提高根管治疗成功率。
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ROLE OF HERBAL EXTRACTS IN ROOT CANAL DISINFECTION AND REMOVAL OF SMEAR LAYER: A REVIEW
Background: The success of endodontic treatment depends on the complete debridement and disinfection of canal space. Various chemicals have been used for canal disinfection. However, to overcome the adverse effects, toxicity issues, and microbial resistance of most conventional canal disinfectants, alternative agents are needed. Many herbal products have been studied and recommended for canal disinfection. This article aimed to review the role of herbal extracts in canal disinfection as an irrigant, intracanal medicament, and their efficacy in smear layer removal. Results: Studies were identified through search of the following electronic databases: PubMed, Science direct, Scopus and Google Scholar. The search was undertaken with keywords herbal agents/ products for root canal disinfection, Enterococcus faecalis, endodontics, smear layer, biofilm, herbal extracts and antimicrobial activity. The literature was reviewed for past 30 years (1990- till June 2020). The results showed that several in-vitro studies reported effective antimicrobial action of herbal extracts for canal disinfection, however, very less in-vivo or clinical studies have been reported to ascertain the use of these agents for endodontic therapy. Conclusions: The study concludes that herbal agents can be effectively used for canal disinfection. However, long-term, invitro, clinical, biocompatibility studies clinical trials are further needed to confidently use these products in endodontics. Herbal extracts can be used as substitute to existing root canal disinfectants due to their unique properties. Therefore, improving the endodontic success rate by preventing root canal failures, persistent and reinfections.
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