全身照射对不同组织的影响。大鼠14C亮氨酸的实验。

V Casati, A Nardino, I Tomassi, A Becciolini, M Rizzi, T Martelli
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引用次数: 2

摘要

分析了注射前2 h接受8gy全身照射的大鼠和对照组对14C亮氨酸的摄取和消除情况。匀浆后测定血浆、小肠、肾脏和皮肤的TCA可溶性活性曲线。在增殖活性差、蛋白质转化率低的高度分化组织中,示踪剂的摄取和消除似乎不受照射的影响。在对照组和受辐射动物的小肠中,差异似乎是显著的。
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Effect of whole body irradiation on different tissues. Experiments with 14C leucine in the rat.

The uptake and elimination of 14C leucine were analysed in controls and in rats irradiated 2 h before injection with 8 Gy whole-body irradiation. Plasma, small intestine, kidney and skin were assayed after homogenization for TCA soluble activity curves. In highly differentiated tissues with poor proliferative activity and low protein turnover, the uptake and elimination of the tracer did not appear to be affected by irradiation. In the small intestine differences between control and irradiated animals seemed significant.

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