c介导的复合物释放活性(CRA)嵌入假说的证据

E´va Rajnavo¨lgyi , G. Fu¨st , Julia Ember , G.A. Medgyesi , J. Gergely
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引用次数: 4

摘要

用Clq或双价葡萄球菌蛋白A预孵育bsa -抗bsa沉淀,由于新鲜血清的补体依赖性复合物释放活性(CRA),抑制了沉淀的增溶作用。抑制作用呈剂量依赖性。结果支持CRA的嵌入假说。
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Evidences proving the intercalation hypothesis of the C-mediated complex release activity (CRA)

Pre-incubation of BSA-anti-BSA precipitates with Clq or bivalentStaphylococcus protein A inhibits the solubilization of the precipitates due to the complement dependent complex release activity (CRA) of fresh sera. The inhibition was dose dependent. The results support the intercalation hypothesis of CRA.

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