镰状细胞肾病中磷酸盐的小管重吸收。

Clinical science and molecular medicine Pub Date : 1978-11-01 DOI:10.1042/cs0550429

P E De Jong, L T de Jong-van Den Berg, L W Statius van Eps

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引用次数: 18

摘要

1. 在一系列镰状细胞性贫血患者中，血清磷酸盐和镁浓度升高。血钙浓度正常。尿钙排泄减少。2. 在这些患者中，每升肾小球滤液中磷酸盐的最大小管重吸收(TmP/GFR)显著增加。3.磷酸盐重吸收的增加解释了在这些患者中观察到的血清磷酸盐升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The tubular reabsorption of phosphate in sickle-cell nephropathy.

1. In a series of patients with sickle-cell anaemia, serum phosphate and magnesium concentrations were elevated. Serum calcium concentrations were normal. Urinary excretion of calcium was decreased. 2. The maximum tubular reabsorption of phosphate per litre of glomerular filtrate (TmP/GFR) was significantly increased in these patients. 3. The increase in phosphate reabsorption explains the elevated serum phosphate observed in these patients.

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