The Genus Corynebacterium in the Genomic Era

This chapter will address the main omics approaches used in studies involving the genus Corynebacterium , Gram-positive microorganisms that can be isolated from many diverse environments. Currently, the genus Corynebacterium has more than 130 highly diversified species, many of which present medical, veterinary and biotechnological importance, such as C. diphtheriae , C. pseudotuberculosis, C. ulcerans and C. glutamicum . Due to the wide application in these fields, several omics methodologies are used to better elucidate the species belonging to this genus, such as genomics, transcriptomics and proteomics. The genomic era has contributed to the development of more advanced and complex approaches that enable the increase of generated data, and consequently the advance on the structural, functional and dynamic knowledge of biological systems. of