{"title":"用SABER模拟神经元","authors":"N. Carnevale, T. Woolf, G. M. Shepherd","doi":"10.1109/IEMBS.1988.95353","DOIUrl":null,"url":null,"abstract":"Hypotheses of neuronal functions that invoke realistic anatomical and biophysical properties must be confirmed by quantitative simulation. Most simulators are unable to emulate biophysical phenomena such as time- and voltage-dependent (active) conductances directly. The authors report how special features of SABER, a new general-purpose simulator, facilitated the modeling of active conductances.<<ETX>>","PeriodicalId":227170,"journal":{"name":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Simulating neurons with SABER\",\"authors\":\"N. Carnevale, T. Woolf, G. M. Shepherd\",\"doi\":\"10.1109/IEMBS.1988.95353\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hypotheses of neuronal functions that invoke realistic anatomical and biophysical properties must be confirmed by quantitative simulation. Most simulators are unable to emulate biophysical phenomena such as time- and voltage-dependent (active) conductances directly. The authors report how special features of SABER, a new general-purpose simulator, facilitated the modeling of active conductances.<<ETX>>\",\"PeriodicalId\":227170,\"journal\":{\"name\":\"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IEMBS.1988.95353\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1988.95353","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hypotheses of neuronal functions that invoke realistic anatomical and biophysical properties must be confirmed by quantitative simulation. Most simulators are unable to emulate biophysical phenomena such as time- and voltage-dependent (active) conductances directly. The authors report how special features of SABER, a new general-purpose simulator, facilitated the modeling of active conductances.<>
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