动静脉瘘在缺血性肢体血运重建中的应用。

S E Cohen, N M Matolo, E F Wolfman
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引用次数: 1

摘要

在使用动静脉瘘血运重建缺血肢体的基本考虑已被总结。动脉血液通过动静脉瘘进入静脉系统的逆行流动已在急性和慢性动物实验中得到证实。虽然在一些小范围的研究中已经有证据表明人类有明显的血流逆转,但它的发生仍然存在争议。静脉瓣膜在即将发生的逆行血流中的意义尚未得到充分的研究。由于外周动静脉瘘是四肢动脉血管形成最有效的刺激因素之一,因此在某些晚期和其他“不能手术”的动脉闭塞性疾病患者中,它的应用可能值得考虑。
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Arteriovenous fistula for revascularization of the ischemic extremity.

The basic considerations in the use of an arterio-venous fistula for revascularization of the ischemic extremity have been summarized. Retrograde flow of arterial blood entering the venous system by way of an arteriovenous fistula has been demonstrated in acute and chronic animal experiments. While evidence of significant reversed flow in humans has been shown in a few small series, its occurrence is still controversial. The significance of venous valves in impending retrograde flow is not yet adequately investigated. Since a peripheral arteriovenous fistula is one of the most potent stimuli to arterial vessel formation in the extremity, its application may be worthy of consideration in certain selected patients with advanced and otherwise "inoperable" arterial occlusive disease.

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