心肌炎相关covid -19 mRNA疫苗接种:叙述性综述

Al- Anbar Medical Journal Pub Date : 2023-06-16 DOI:10.33091/amj.2023.139728.1106

Idman Gushaendri, Faiza Shafia, N. Hairunisa, E. Yousif, Husnun Amalia

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摘要

冠状病毒病-19 (COVID-19)大流行对社会和全球经济的前所未有的影响凸显了对有效和安全疫苗的迫切需要。这种疫苗的一个非常罕见的副作用是心肌炎，这被认为是COVID-19 mRNA疫苗的可怕并发症。最近的一项研究显示，VAERS报告的心肌炎事件增加了1824例，单剂接种后报告了383例(21.00%)，注射第二剂后报告了956例(52.41%)。最常见的主诉是注射后一周内出现胸痛。年轻和男性患者发病率高。mrna接种后心肌炎的病理生理机制尚不清楚，一项研究假设是由于超敏性心肌炎，另一项研究表明另一种可能的机制是分子模仿。本文献综述的主要目的是提高认识，预防

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Myocarditis Related-COVID-19 mRNA Vaccination: A Narrative Review

The unprecedented impact of the coronavirus disease-19 (COVID-19) pandemic on society and the global economy has highlighted the urgent need for an eﬀective and safe vaccine. One of the very rare side eﬀects of this vaccine is myocarditis, which was realized to be a terrible complication of the COVID-19 mRNA vaccine. A recent study showed an increase in 1824 events of myocarditis re-ported to VAERS, 383 (21.00%) reported after receiving a single dose of vaccine, then 956 (52.41%) after injection of the second dose. The most common complaint is chest pain that appears within 1 week after the injection. Young and male patients have a high incidence. The pathophysiology of post-mRNA vaccination myocarditis remains unclear, with one study hypothesizing it to be due to hypersensitivity myocarditis and another study suggesting another possible mechanism is molecular mimicry. The main aim of this literature review is to improve knowledge, prevention

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Al- Anbar Medical Journal

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