应该恢复诊断阴道炎的侧实验室检查吗?

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摘要

摘要背景:阴道分泌物是妇科门诊患者最常见的主诉之一,临床诊断仍具有主观性,因此本研究将临床诊断与单纯侧检进行比较,并将拭子送到微生物实验室进行进一步评估,并将结果进行比较,以评估是否可以提高诊断。材料和方法:收集100例有阴道分泌物的性活动性患者阴道拭子,在微生物科实验室进行湿载(直接镜检和KOH载)、pH值测试和Whiff测试(标记为推定诊断的侧实验室测试)及相关培养。结果:临床诊断与最终实验室诊断相关性较差(19%)(kappa系数0.1982)。这可能会影响仅根据临床(视觉)检查提供的治疗。然而,在假定和最终实验室诊断之间观察到非常令人欣慰的相关性(71%)(kappa系数= 0.7149)。这些侧实验室检查对生理性分泌物、细菌性阴道病、念珠菌病、混合性阴道炎、滴虫病的诊断准确率分别为84%、88%、95.1%、89%和98%。结论:简单的侧室检查提高了阴道炎的诊断,应纳入所有教学和三级保健中心,以更好地管理阴道炎。
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Should Side Lab Tests for Diagnosis of Vaginitis Be Resumed.
Abstract Background: Vaginal discharge is one of the most common complaint of patients presenting in Gynecology OPD and clinical diagnosis remains subjective, hence the present study was conducted to compare clinical diagnosis with simple side lab tests with swabs sent to microbiology laboratory for further evaluation and results compared to evaluate whether diagnosis can be improved. Material and methods: Vaginal swabs were collected from 100 sexually active patients presenting with vaginal discharge for Wet mount (direct microscopy and KOH mount), pH test and Whiff test (labeled as side lab test for presumptive diagnosis) and for relevant cultures in laboratory of microbiology Department. Results: The study revealed poor correlation (19%) between clinical diagnosis and final laboratory diagnosis (kappa coefficient 0.1982). This may effect treatment provided only on the basis of clinical (visual) examination. However, very encouraging correlation (71%) was observed between presumptive and final lab diagnosis (kappa coefficient= 0.7149) The diagnostic accuracy of these side lab tests for physiological discharge, bacterial vaginosis, candidiasis, mixed vaginitis, trichomoniasis was 84%, 88%, 95.1%, 89% and 98%, respectively, in reference to final lab tests. Conclusion: Simple side lab tests improve diagnosis of vaginitis and should be incorporated in all teaching and tertiary care centers for better management of vaginitis.
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