抗小鼠抗胸腺细胞马血清致敏性研究。

Annales immunologiae Hungaricae Pub Date : 1975-01-01
E Osz, L Réthy
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引用次数: 0

摘要

作者比较了小鼠主动致敏和被动致敏引起的过敏反应。在主动致敏的情况下,使用抗小鼠抗胸腺细胞马血清(ATS)和/或正常马血清(NHS),而在被动致敏的情况下,使用致敏动物的血浆、外周血白细胞、脾脏细胞和胸腺细胞。通过静脉注射ATS或NHS引发休克。不可逆的过敏反应发生在ATS的情况下明显高于NHS敏感性,无论是主动还是被动产生。4种材料的被动转移效能也存在差异。
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The sensitizing properties of anti-mouse anti-thymocyte horse serum.

The authors have compared the anaphylaxis due to active and passive sensitization of mice. In the case of active sensitizing, anti-mouse anti-thymocyte horse serum (ATS), and/or normal horse serum (NHS), whereas in the case of passive sensitizing, plasma, peripheral leukocytes, spleen cells and thymocytes of sensitized animals were used. Provocation of shock was carried out by intravenous administration of ATS or NHS. Irreversible anaphylaxis occurred in a significantly higher rate in the case of ATS than NHS sensitivity, produced either actively, or passively. Differences have been found also between the 4 investigated materials according to their passive transfer potency.

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