Ainur Orazayeva, J. Tussupov, S. Pavlov, S. Tymchyk, N. Savina, O. S. Bezkrevnyi
{"title":"基于多元回归的乳腺癌患者BRCA1和TP53基因型与肿瘤组织学类型关系的数学模型","authors":"Ainur Orazayeva, J. Tussupov, S. Pavlov, S. Tymchyk, N. Savina, O. S. Bezkrevnyi","doi":"10.31649/1681-7893-2021-41-1-59-68","DOIUrl":null,"url":null,"abstract":"The article analyzes the growing incidence of breast cancer, which has become particularly clear in the last two decades, requires special involvement of all specialists and researchers in this area. Identification of patients with hereditary forms of breast cancer allows to form strategies for early diagnosis, prevention and treatment. As a result of the analysis, the multiple regression equation was obtained.The statistical significance of the equation was verified using the coefficient of determination and Fisher's test. Prompt diagnosis should be combined with effective cancer treatment, which in many cases requires specialized cancer care at some level. Thanks to the creation of centralized services in oncology facilities or hospitals, which use as a model everything related to breast cancer, the treatment of breast cancer can be optimized while improving the treatment of other cancers.","PeriodicalId":142101,"journal":{"name":"Optoelectronic information-power technologies","volume":"3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mathematical model of the relationship between the genotype of patients with breast cancer on BRCA1 and TP53 and histological type of tumor based on multiple regression\",\"authors\":\"Ainur Orazayeva, J. Tussupov, S. Pavlov, S. Tymchyk, N. Savina, O. S. Bezkrevnyi\",\"doi\":\"10.31649/1681-7893-2021-41-1-59-68\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The article analyzes the growing incidence of breast cancer, which has become particularly clear in the last two decades, requires special involvement of all specialists and researchers in this area. Identification of patients with hereditary forms of breast cancer allows to form strategies for early diagnosis, prevention and treatment. As a result of the analysis, the multiple regression equation was obtained.The statistical significance of the equation was verified using the coefficient of determination and Fisher's test. Prompt diagnosis should be combined with effective cancer treatment, which in many cases requires specialized cancer care at some level. Thanks to the creation of centralized services in oncology facilities or hospitals, which use as a model everything related to breast cancer, the treatment of breast cancer can be optimized while improving the treatment of other cancers.\",\"PeriodicalId\":142101,\"journal\":{\"name\":\"Optoelectronic information-power technologies\",\"volume\":\"3 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Optoelectronic information-power technologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31649/1681-7893-2021-41-1-59-68\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optoelectronic information-power technologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31649/1681-7893-2021-41-1-59-68","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mathematical model of the relationship between the genotype of patients with breast cancer on BRCA1 and TP53 and histological type of tumor based on multiple regression
The article analyzes the growing incidence of breast cancer, which has become particularly clear in the last two decades, requires special involvement of all specialists and researchers in this area. Identification of patients with hereditary forms of breast cancer allows to form strategies for early diagnosis, prevention and treatment. As a result of the analysis, the multiple regression equation was obtained.The statistical significance of the equation was verified using the coefficient of determination and Fisher's test. Prompt diagnosis should be combined with effective cancer treatment, which in many cases requires specialized cancer care at some level. Thanks to the creation of centralized services in oncology facilities or hospitals, which use as a model everything related to breast cancer, the treatment of breast cancer can be optimized while improving the treatment of other cancers.